Results 51 to 60 of about 739,113 (267)

Factors Associated with Seasonal Influenza Non-Vaccination Among Children with Chronic Health Conditions in Canada: A Cross-Sectional Study

Vaccines
Background/Objectives: Seasonal influenza vaccination is pivotal for protecting high-risk populations, including those with chronic health conditions (CHCs), from severe complications and outcomes.
Arlanna Pugh, Sailly Dave, Marwa Ebrahim, Julie A. Laroche   +3 more
doaj   +1 more source

Writing the River

Open Rivers, 2018
What does the river say to you? This is the core question posed by Write to the River, a creative writing project that I launched in partnership with the Twin Cities nonprofit Friends of the Mississippi River and photographer Tom Reiter, in spring 2017.
Leslie Thomas
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Water Unifies Us All

Open Rivers, 2018
A dominant narrative in media today tells us that American society is full of juxtaposition and conflict: rural v. urban, rich v. poor, black v. white, conservative v. liberal.
Kristi Achor Pursell
doaj   +1 more source

The National Endowment for the Humanities : un levier fédéral des musées amérindiens

Revue LISA, 2007
The National Endowment for the Humanities (NEH) is a federal agency created in 1965 with the mission of “serving the nation by promoting the humanities and giving lessons of history to all Americans.” It finances radio and TV programs on history, music ...
Gérard Selbach
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Protection of savings by reducing the salience of opposing errors

npj Science of Learning
When humans encounter the same perturbation twice, they typically adapt faster the second time, a phenomenon called savings. Studies have examined savings following adaptation to a gradually introduced perturbation, with mixed results.
Mousa Javidialsaadi, Scott T. Albert, Badr Moufarrej S Al Mutairi, Jinsung Wang   +3 more
doaj   +1 more source

Exploring Perception of Menopausal Symptoms and Social Support Seeking Behavior among Post-menopausal Women: A Qualitative Study

Journal of Nepal Medical Association
Introduction: Menopause is a natural phenomenon, however symptoms persist in many women. Geographical location and individual factors influence the perception and care-seeking behavior.
Pratiksha Paudel, Shristi Thapa, Bipsana Shrestha, Shrinkhala Shrestha   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source