Results 71 to 80 of about 13,874,377 (264)

Attitudes and information-needs towards a risk-based optimization of colorectal cancer screening among Danish citizens: a qualitative study

open access: yesDiscover Public Health
Background Colorectal cancer (CRC) screening programs in many countries often adopt a one-size-fits-all approach, commonly utilizing the Fecal Immunochemical Test (FIT).
Signe Bülow Therkildsen   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Self-Government and the Prohibition of General Elections Under Baduy-Dalam Customary Law

open access: yesJurnal Ilmiah Ilmu Administrasi Publik
This article discusses the implementation of self-governance using customary law within the Baduy-Dalam Traditional Law Community (KMHA). The author's interest in studying the Baduy-Dalam stems from the bias in understanding between the KMHA, Villages ...
Jumanah Jumanah, Arif Nugroho
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Building data science capacity in the public health workforce: a Public Health Data Science Life Cycle framework

open access: yesFrontiers in Public Health
The digital transformation of public health systems has increased the need for a workforce capable of using data science to inform population health decision-making.
Emily M. Burke   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Risk factors associated with the intensity of COVID-19 outbreaks in Canadian community settings: a retrospective analysis of outbreak-level surveillance data

open access: yesBMC Public Health
Background The severity of COVID-19 outbreaks is disproportionate across settings (e.g., long-term care facilities (LTCF), schools) across Canada. Few studies have examined factors associated with outbreak severity to inform prevention and response.
Demy Dam   +9 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Self insurance and public employment programs [PDF]

open access: yes
The paper studies the labor allocation decision by households faced with non-insurable labor income risks and establishes a case for a government sponsored public employment program as a provider of self-insurance to such households.
Sunanda Roy
core  

IDENTIFYING THE PUBLIC VALUE IN EXTENSION PROGRAMS [PDF]

open access: yes
Government budget crises have compelled state Extension Services to defend their receipt of state and county funding. A key to that defense is persuading citizens and policymakers of Extension's "public value": the benefit from Extension programs to ...
Kalambokidis, Laura
core   +2 more sources

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