Results 161 to 170 of about 967,180 (294)

Fiscal Year 1959

, 1959
Annual financial report of the Texas Department of Public Safety documenting income, expenditures, and other relevant financial information for fiscal year ...
Texas. Department of Public Safety.
core  

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Empathy in Public Safety: Selection Standards, Gender Differences, and Relations with Existing Selection Predictors. [PDF]

J Funct Morphol Kinesiol
Milošević MM, Koropanovski N, Vuković M, Mudrić MR, Kukić F, Ristić I, Stamatis A, Dopsaj M.   +7 more
europepmc   +1 more source

Fiscal Year 2017

, 2017
Annual financial report of the Department of Public Safety documenting income, expenditures, and other relevant financial information for fiscal year ...
Texas. Department of Public Safety.
core  

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

3MDR Therapy Reduces Symptoms of PTSD and Related Conditions in Canadian Military Members and Veterans, Public Safety Personnel, and Clinical Personnel. [PDF]

Brain Behav
Brown MRG, Sevigny PR, Bright KS, Chau H, Chai P, Greenshaw AJ, Burback L, Winkler O, Jones C, Brémault-Phillips S.   +9 more
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Emergency Department Visits During the Fall 2019 Public Safety Power Shutoff Events in California. [PDF]

Disaster Med Public Health Prep
Harding AB, Berman JD, Tarr GAM, Erickson DJ, Ramirez MR.   +4 more
europepmc   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

"It Was a Very Pleasant Surprise": Exploring Public Safety Service Users' Experiences With Inpatient Mental Health Treatment and Recovery. [PDF]

J Clin Psychol
Johnston MS, Ricciardelli R, Vester E, Martin K.   +3 more
europepmc   +1 more source