Results 51 to 60 of about 3,337,668 (303)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Strengthening public safety nets [PDF]
Helping to reduce vulnerability poses a new set of challenges for public policy. The most immediate challenge is to determine the appropriate role for public action if there should be a role at all.
Morduch, Jonathan, Sharma, Manohar
core +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Psychological components of police care as a factor of guaranteeing public safety
Law and Safety, 2018 The application of police care as a completely new measure for Ukraine has been analyzed. This measure appeared on the list of preventive police measures (c. 11, Part 1 of the Art.
H. V. Dzhahupov
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
IEEE Access, 2019 This paper introduces a unified representation for collaborative development of complex services in public safety to explain the infusion of digital technologies into the design of the community resilience processes with respect to the potential ...
Monica Dragoicea +3 more
doaj +1 more source
, 2023 The article is devoted to the problem of ensuring public safety. The issues of normative legal acts that form the legal basis of this area of ensuring national security, its threats, as well as measures to prevent and prevent them are considered in detail. The issues of ensuring public safety and its necessity are revealed, especially in the context of
A.A. Madjara, E.Yu. Selezneva
openaire +1 more source
How Mobile Devices are Transforming Disaster Relief and Public Safety [PDF]
, 2013 With its growing usage, mobile technology is greatly improving disaster relief and public safety efforts. Countries around the world face threats from natural disasters, climate change, civil unrest, terrorist attacks, and criminal activities, among ...
Darrell M. West, Elizabeth Valentini
core
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Joint Committees: No Substitute for Union Action [PDF]
, 1990 [Excerpt] Nearly half of all industrial union contracts mandate joint labor-management health and safety committees (JHSCs). In the past five years, mandated JHSCs have also become common in the public sector in states that have enacted occupational ...
Egarian, Marjorie
core +1 more source