Results 41 to 50 of about 2,927,610 (300)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Designing and Operating Safe and Secure Transit Systems: Assessing Current Practices in the United States and Abroad, MTI Report 04-05 [PDF]

, 2005
Public transit systems around the world have for decades served as a principal venue for terrorist acts. Today, transit security is widely viewed as an important public policy issue and is a high priority at most large transit systems and at smaller ...
Cavanagh, Ellen, Cherry, Christopher, Fink, Camille, Haas, Peter J, Liggett, Robin, Loukaitou-Sideris, Anastasia, Taylor, Brian D., Wachs, Martin   +7 more
core   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

Making Security Interests Public [PDF]

, 2012
Movable assets tangible or intangible often account for most of firm's capital stock. Thus it is important for jurisdictions to develop adequate laws on secured transactions to allow borrowers and lenders to recognize movable assets as collateral, supporting financing secured with such assets.
Downes, Santiago Croci, Hennig, Betina Tirelli, Alvarez de la Campa, Alejandro   +2 more
openaire   +3 more sources

Criminal Trajectory Reconstruction Method Based on a Mobile Reference System

Computational Urban Science
Criminal trajectory reconstruction is a crucial area of study in the investigative and evidentiary processes of public security departments. This paper proposes a method for reconstructing criminal trajectories based on a mobile reference system ...
Zhengyan Ding, Yan Lin, Xin Wei Li, Cheng Rui Gu, Qi Yan Ying   +4 more
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Lightweight deep learning model for crime pattern recognition based on transformer with simulated annealing sparsity and CNN

Scientific Reports
This study addresses the pressing need for high efficiency and low resource consumption in crime pattern recognition within public safety governance by proposing a lightweight deep learning model known as the lightweight crime recognition network (LCRNet)
HongYuan Lu, ChengXin Chen, YuQi Ma, YanMing Ma   +3 more
doaj   +1 more source

Research on Hybrid Recommendation Model for Personalized Recommendation Scenarios

Applied Sciences, 2023
One of the five types of Internet information service recommendation technologies is the personalized recommendation algorithm, and knowledge graphs are frequently used in these algorithms.
Wenkai Ni, Yanhui Du, Xingbang Ma, Haibin Lv   +3 more
doaj   +1 more source

The Social Security Benefits of Sitting Senators [PDF]

, 2011
In November, Colorado Senator Michael Bennet was interviewed on National Public Radio's Morning Edition by Renee Montagne. In the course of the interview, Senator Bennet told Ms. Montagne that, as a 45-year old, he would get no Social Security benefit if
Dean Baker, Kris Warner
core