Results 241 to 250 of about 5,760,794 (363)

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

Advanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu, Chao Xue, Yang Zhao, Jinjian Sun, Changzhi Zhao, Xu Zhang, Guizhen Zhao, Yaozhong Liu, Hongyu Liu, Yongjie Deng, Ying Wang, Chi Zhang, Yingjie Liu, Linjun Zeng, Ying Yang, Bolun Li, Shusi Ding, Linkang Zhou, Henry Kuang, Zanxin Wang, Wenhao Ju, Haihuan Lin, Jie Lin, Yanhong Guo, Lin Chang, Hongmei Zhao, Jing Wang, Jiandie Lin, Lemin Zheng, Y. Eugene Chen, Jifeng Zhang   +30 more
wiley   +1 more source

Barriers to seeking consultation at public service and medical facilities among pregnant and postpartum women in Japan: a cross-sectional study. [PDF]

PeerJ
Okawa S, Seino K, Iso H, Tabuchi T.
europepmc   +1 more source

The Effects of Privatization of Public Services: The Case of Urban Water

, 2000
Charles W. Howe
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Factors influencing sustainable E-participation in public service delivery: A case of rail infrastructure project. [PDF]

Heliyon
Pai RR, Alathur S.
europepmc   +1 more source

Democracy, deliberation and public service reform: The Case of NICE

, 2013
Annabelle Lever
openalex   +1 more source

Work Ethics, Values, Attitudes and Performance In The Nigerian Public Service: Issues, Challenges and The Way Forward

, 2015
Bernard Oladosu Omisore, Oyende Adeleke A.   +1 more
openalex   +2 more sources

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids

Advanced Science, EarlyView.
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang, Tsering Yangzom, Ning Lu, Shenglong Deng, Xianglu Xiao, Guang Yang, Kristina Xiao Liang   +6 more
wiley   +1 more source

Correction to: Peer-led public service announcement creation workshops for adolescent sexual and reproductive health education in Kenya. [PDF]

Health Promot Int
europepmc   +1 more source

Has urban public service equalization reduced regional differences in economic resilience? [PDF]

PLoS One
Wang S, Zhang Q, Sun M, Teng Y.
europepmc   +1 more source