Advanced Science, EarlyView.In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Embrace or leave social media? On the viability of public service media organizations' strategies facing platform power. [PDF]
Eur J CommunMoe H.
europepmc +1 more source
Advanced Science, EarlyView.This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu +12 more
wiley +1 more source
The Antecedents and Outcomes of Public Service Motivation: A Meta-Analysis Using the Job Demands-Resources Model. [PDF]
Behav Sci (Basel)Tang H, An S, Zhang L, Xiao Y, Li X.
europepmc +1 more source
Advanced Science, EarlyView.Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
Correction: A study of market segmentation, government competition, and public service efficiency in China: Based on a semi-parametric spatial lag model. [PDF]
PLoS OneYao L, Luo R, Yi X.
europepmc +1 more source
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Advanced Science, EarlyView.Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Genetic Diagnosis and Discovery Enabled by Large Language Models
Advanced Science, EarlyView.We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
Was health skepticism accounted for in communication about the COVID-19 vaccine? A content analysis of federally-sponsored public service announcements about the vaccine to protect against COVID-19 in the United States. [PDF]
Prev Med RepTait ME, Fowler EF, Gollust SE.
europepmc +1 more source
Evaluation of privacy protection methods of public service advertising visual design in the perspective of artificial intelligence internet of things. [PDF]
PLoS OneTang X.
europepmc +1 more source