Results 51 to 60 of about 5,859,837 (360)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Judge Parker and the Public Service State [PDF]
The work described in this thesis is part of the Open Space project, a collaboration between Linköping University, NASA and the American Museum of Natural History.
Fish, Peter G.
core +2 more sources
A machine learning-based short-term forecasting method for heavy fog in Anhui Province of China
Based on hourly observations from expressway meteorological stations across Anhui Province and the fifth-generation atmospheric reanalysis (ERA5) data from the European Centre for Medium-Range Weather Forecasts (ECMWF) spanning from January 2011 to ...
Yan Sun +5 more
doaj +1 more source
Virucidal efficacy of guanidine-free inactivants and rapid test buffers against SARS-CoV-2
A pathogen inactivation step during collection or processing of clinical samples has the potential to reduce infectious risks associated with diagnostic procedures.
Katherine Davies +16 more
doaj +1 more source
Crowding out public service motivation [PDF]
Employing workers with Public Service Motivation (PSM) has been proposed as a means of improving performance in the public sector. There is, however, no conclusive evidence showing PSM among individuals.
Georgellis, Y, Iossa, E, Tabvuma, V
core
Why Would Anyone Want to Be a Public Interest Lawyer? [PDF]
I can barely express how grateful the Law Center is to the Delaneys for their generous gift, or what an honor it is to be designated as the first Delaney Family Professor of Public Interest Law at this incredibly vibrant institution. But our celebration
Schrag, Philip G.
core +3 more sources
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Public Service Motivation concept was developed in North America and focuses on specific motivations of public servants, such as employee satisfaction, organizational commitment, reward preferences, organizational and individual performance.
Raluca-Marilena Mihalcioiu
doaj

