Results 51 to 60 of about 1,619,727 (310)
PUBLIC SERVICES PROVISION OF ADMINISTRATIVE SERVICES [PDF]
Management Intercultural, 2014 Public services are somehow directly related to the authorities of public administration, which assume their responsibility for its activity in front of public opinion. The public service fulfils the general interest mission, being vested with prerogatives of political power.
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A call for conceptual clarity: a soft systems view of performance measurement in public service delivery [PDF]
, 2005 Performance measurement systems and the publication of performance data are fundamental to the New Public Management, with its emphasis on decentralised service provision through a variety of agencies.
Pidd, M
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
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M@n@gementHow meta-organizations (MOs) can be engaged in competitive settings remains an underexplored issue, largely because scholars have traditionally emphasized MOs’ tendency toward monopoly (Ahrne & Brunsson, 2005) and focused on potential internal tensions ...
Pierre Garaudel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
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Performance paradoxes: The politics of evaluation in public services [PDF]
, 2008 About the book: Public Services Inspection in the UK provides a detailed account of the changing role of inspection in public services management. It outlines the continuing debates about providing inspection that encourages not only accountability but ...
Clarke, John
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Market Mechanisms in Public Service Provision [PDF]
OECD Economics Department Working Papers, 2008 This paper presents a new set of institutional indicators that assess how sub-central governments harness market mechanisms such as tendering, outsourcing, user choice and competition, user fees and output-related funding when providing public services.
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
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