Results 81 to 90 of about 5,782,213 (317)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Nature of a Public Service [PDF]
International Journal of Public Administration, 2009 Abstract Public services have been misunderstood. They are not simply services in the public sector, they are not necessarily there because of “market failure”, and they cannot be analysed by the same criteria as market-based provision. They have four defining characteristics.
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Public Libraries and the Internet 2006 [PDF]
, 2006 Examines the capability of public libraries to provide and sustain public access Internet services and resources that meet community needs, including serving as the first choice for content, resources, services, and technology ...
Charles R. McClure +3 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Justice Data Base Directory [PDF]
, 1992 The Justice Data Base Directory was originally published in 1988 with an introduction, 8 chapters describing Alaska justice agencies and their data holdings, and an index. It was published in looseleaf notebook format for easy updating. Four updates were
Alaska Justice Statistical Analysis Unit +1 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Archives of Public Health, 2020 In the original publication of this article [1], the author pointed out the legends of Figs. 1 and 2 are not entire. The correct legends are:
Grant M. A. Wyper +5 more
doaj +1 more source
Publics, politics and power: Remaking the public in public services
, 2009 Challenges the notion that publicness and the public sphere is in decline, and analyses the emergence of new forms, sites and practices of publicness and the implications for public services.
Clarke, John, Newman, Janet
core +1 more source