Results 51 to 60 of about 15,429,640 (279)

Queering Public Space: Exploring the relationship between queer communities and public spaces [PDF]

open access: yes, 2021
This report explores a number of factors which might contribute to making public space safer and more inclusive for all, not least LGBTQ+ people. It examines issues including the rise of the gayborhood, the location of hate crimes and incidents, the ...
Azzouz, Ammar, Catterall, Pippa
core   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Recalling the Political in Public Space

open access: yes, 2014
The history of public space is often the same history as discrimination and revolts. It is because public spaces are intended to be open-ended, in order for the public to enjoy and express themselves. In societies where the government is put in place and
H. KOON WEE, Wee, HK
core   +1 more source

Public Space in Planning Traditions [PDF]

open access: yesبرنامه‌ریزی توسعه شهری و منطقه‌ای
Public spaces have important role in city life, are so effective for cities for appropriate quality of life and economic, social and cultural development.
Hesam Hassanipour   +1 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Chapter 1: Ottoman women in public space: an introduction

open access: yes, 2016
sing a wealth of primary sources and covering the entire Ottoman period, Ottoman Women in Public Space challenges the traditional view that sees Ottoman women as a largely silent element of society, restricted to the home and not seen beyond the walls of
Fleet, Kate   +4 more
core   +1 more source

EL ESPACIO PÚBLICO EN DISPUTA. EL CASO DE LA CALLE DE ACCESO AL CAMPUS DE LA UNIVERSIDAD NACIONAL DEL COMAHUE [PDF]

open access: yesBoletín Geográfico, 2016
The urban space bears profound transformations, which also lead to reformulations of public space in terms of ownership, access and use. The article introduces a process of reflection taking as an example the order that the Municipality of the city of ...
Romina V. Schroeder
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Visibility and the Policing of Public Space [PDF]

open access: yes, 2011
From studies of ‘panoptic’ CCTV surveillance to accounts of undercover police officers, it is often mooted that visibility and invisibility are central to the policing of public space.
Laing, Mary, Cook, Ian
core   +1 more source

Home - About - Disclaimer - Privacy