Results 21 to 30 of about 191,808 (298)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Public Libraries as Agonistic Spaces

Libellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2021
The paper deals with the possibilities of engaged interdisciplinary activity implemented at the crossroads of librarianship and contemporary art practices.
Irena Bekić, Petra Dolanjski
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Models for Positioning Public Spaces in the Metaverse

Journal of Technology in Architecture Design and Planning
The Metaverse plane constitutes an ever-evolving virtual universe that encompasses various digital platforms. These platforms allow users to engage in diverse experiences and create virtual environments using technologies such as virtual reality ...
Ezgi Özkoç, Şan Yalçın Sarabil
doaj   +1 more source

Demographic Groups’ Differences in Restorative Perception of Urban Public Spaces in COVID-19

Buildings, 2022
The health-promoting functions of one’s spatial environment have been widely recognized. Facing the huge loss of mental resources caused by the COVID-19 pandemic, visiting and perception of urban public spaces with restorative potential should be ...
Shiqi Wang, Ang Li
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Quantitative Evaluation of Spatial Differentiation for Public Open Spaces in Urban Built-Up Areas by Assessing SDG 11.7: A Case of Deqing County

ISPRS International Journal of Geo-Information, 2020
Urban public open spaces refer to open space between architectural structures in a city or urban agglomeration that is open for urban residents to conduct public exchanges and hold various activities.
Qiang Chen, Mingyi Du, Qianhao Cheng, Changfeng Jing   +3 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Lovers and City A Study about Youth and Uses of Public Spaces [PDF]

Taḥqīqāt-i Farhangī-i Īrān, 2016
There has been a huge concern about the manner of confrontations of different social groups with urban public spaces within urban scholars. Among these social groups, young people have been particularly important. Because they have a tangible presence in
Fardin Alikhah, Masomeh Shadmanfaat
doaj   +1 more source