Results 71 to 80 of about 973,057 (311)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Internet as a “Public Sphere”
Žurnalistikos Tyrimai, 2011 This paper considers the theory of the Internet becoming part of the “public sphere”. The first part of the paper looks at how the concept of the public sphere was used by different scholars and how they defined the theory of the “public sphere”.
Jurgita Matačinskaitė
doaj +1 more source
Discursive Governance in Politics, Policy and the Public Sphere [PDF]
, 2015 Discursive governance refers to implicit mechanisms of governance such as narratives, leitmotifs, and strategic metaphors in political language. It examines how the framing of policies affects political and social representations in accordance with the ...
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The SPHERE data center: a reference for high contrast imaging processing [PDF]
, 2017 The objective of the SPHERE Data Center is to optimize the scientific return of SPHERE at the VLT, by providing optimized reduction procedures, services to users and publicly available reduced data. This paper describes our motivation, the implementation
Albert, D. +21 more
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FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
The European Journal of Humour ResearchIn this article, which serves as an introduction to a special issue on humor and the public sphere, we argue that humor has become increasingly central to public discourse in the 21st century, and that this necessitates a rethinking of the relationship ...
Giselinde Kuipers, Dick Zijp
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Remarks on network public theory
Managerial Economics, 2014 This paper is a trial of capturing of a relation between traditional public sphere atrophy and the augmentation of a network public sphere. A thesis is advanced that the traditional public sphere is subject of the atrophy, however, the entire network ...
Marcin Brol, Sławomir Czetwertyński
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The making of a state-centered "public sphere" in Turkey : a discourse analysis [PDF]
Why is it that state-centered recognition of the public sphere has prevailed in Turkey during the last decade? The frame analysis of the “public sphere†discourse during the 2002-2009 period revealed that the contingency of the discourse on the ...
Hazama, Yasushi
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Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source