Results 101 to 110 of about 502,123 (307)

Capturing in-situ Feelings and Experiences of Public Transit Riders Using Smartphones [PDF]

, 2017
High-density urban environments are susceptible to ever-growing traffic congestion issues, which speaks to the importance of implementing and maintaining effective and sustainable transportation networks.
Said, Rafik, Said, Rafik
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Transportation assimilation revisited: New evidence from repeated cross-sectional survey data.

PLoS ONE, 2018
BackgroundBased on single cross-sectional data, prior research finds evidence of "transportation assimilation" among U.S. immigrants: the length of stay in the U.S. is negatively correlated with public transit use.
Dafeng Xu
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

A Geospatial Analysis of Freestanding and Hospital Emergency Department Accessibility via Public Transit

Western Journal of Emergency Medicine, 2019
Introduction: Emergency departments (ED) are an important source of care for underserved populations and represent a significant part of the social safety net.
Lucas C. Carlson, Olesya N. Baker, Jeremiah D. Schuur   +2 more
doaj   +1 more source

Examination of Regional Transit Service Under Contracting: A Case Study in the Greater New Orleans Region, Research Report 10-09 [PDF]

, 2011
Many local governments and transit agencies in the United States face financial difficulties in providing adequate public transit service in individual systems, and in providing sufficient regional coordination to accommodate transit trips involving at ...
Houtman, Rebecca, Iseki, Hiroyuki, Rivasplata, Charles R., Smith, Adam L.   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Air pollution hindering a transit-oriented city: Examining the association of particulate matter concentration with public transit ridership and road traffic in Seoul, South Korea

Journal of Public Transportation
In high-density metropolitan areas prone to air pollution, public transit may be less preferred when air quality is poor due to the difficulty of avoiding outdoor air exposure during their use.
Seung-Nam Kim, Sunwoo Jung, Youngha Joo, Hyungkyoo Kim   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source