Results 81 to 90 of about 57,554 (264)

Using Sustainability Indicators to Improve Access to Public Transit in Rural Residential Areas: Alternatives for the Georgia Basin, British Columbia

open access: yesJournal of Rural and Community Development, 2006
The consequence of our dependency on the private automobile is well documented in the literature. Roadway congestion, injurious and lethal traffic accidents, atmospheric pollution, groundwater contamination, suburban sprawl, social inequity, and fossil ...
Robert J Patrick, Mark Roseland
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analysis of Multi-Modal Public Transit Competing Relationships and Evolutionary Mechanisms in Cities in Cold Regions

open access: yesApplied Sciences
In order to reveal the characteristics of the competition and cooperation of multi-modal public transportation in the cities of cold areas and to study the competitive relationship of multi-modal public transportation in cold areas, the urban public ...
Yulong Pei, Wanjiao Wang
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

When Public Transit Stops, Bikes Roll: Measuring the Impacts of Public Transit Strikes on Bicycle Sharing use in Montréal

open access: yesFindings
Public transit strikes reduce bus and metro service, prompting reliance on other modes of transport such as bicycle-sharing and testing the resilience of the transport system.
Hisham Negm, Ahmed El-Geneidy
doaj   +1 more source

Research on Urban Rail Transit 5G Public-private Network Wireless Coverage Scheme

open access: yesChengshi guidao jiaotong yanjiu
Objective The urban rail transit 5G public-private network (PPN) is a vertical application of 5G public network in urban rail transit industry, which differs significantly from the wireless coverage scheme of the 5G public network when only catering to ...
Weijun LIU
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Spatial heterogeneity of horizontal and vertical demand supply equity on public transit

open access: yesKSCE Journal of Civil Engineering
Public transit is an essential transportation service that ensures everyone’s right to travel and must be provided equitably to all users. To achieve this, many jurisdictions are conducting studies to establish equity in public transportation.
Nayeon Kim   +4 more
doaj   +1 more source

Transportation assimilation revisited: New evidence from repeated cross-sectional survey data.

open access: yesPLoS ONE, 2018
BackgroundBased on single cross-sectional data, prior research finds evidence of "transportation assimilation" among U.S. immigrants: the length of stay in the U.S. is negatively correlated with public transit use.
Dafeng Xu
doaj   +1 more source

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