Results 61 to 70 of about 57,639 (264)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Access to Public Transit and Its Influence on Ridership for Older Adults in Two U.S. Cities
Journal of Transport and Land Use, 2009 Growth in the population of older adults (age 60 and above) in coming years will challenge urban planners and transportation managers to provide travel options that support autonomy.
Daniel Baldwin Hess
doaj +1 more source
The Transitional Public School.
Journal of Educational Sociology, 1935 "An attempt to reconcile and harmonize and mediate the subject-centered public school and the 'child-centered' activity experimental school."--Pref. ; Includes bibliographies. ; Mode of access: Internet.
Mead, Cyrus De Witt, 1875- +1 more
openaire +2 more sources
The Public Consciousness of the Transition
Studia Universitatis Babeş-Bolyai Dramatica, 2022 "The decade following the Romanian Revolution, generally known as “the transition,” saw radical changes in the economic and social fabric of the country, with one apparent exception: the public theatre system. At the same time, the monopoly the winners of post-communism developed on the discourse about the transition and the traditional practices of ...
openaire +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Urban ScienceThis study investigates the effects of transportation, specifically public transit, the built environment, and sociodemographic factors on community quality of life (QOL) and individuals’ overall life satisfaction (OLS) in the United States.
Muhammad Asif Khan +3 more
doaj +1 more source
Understanding social media program usage in public transit agencies
International Journal of Transportation Science and Technology, 2016 Social media has been gaining prominence in public transit agencies in their communication strategies and daily management. This study aims to better understand recent trends in social media usage in public transit agencies, to examine which agencies use
Jenny H. Liu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source