Results 51 to 60 of about 87,532 (312)

Modeling the impact of e-hailing services on regional public transit considering transit-dependent people

open access: yes, 2023
We propose an analytical model to theoretically and numerically examine the impact of the introduction of e-hailing services into a region with traditional public transit, considering transit-dependent people who cannot drive themselves.
Hayakawa, Keiichiro, Chikaraishi, Makoto
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

What motivates public support for public transit?

open access: yes, 2018
Voters often support increased spending for public transportation, but the motivation behind this support is as hard to discern as it is substantively important. Why do voters support transit? We use a survey-framing experiment (n = 1200) to evaluate the
Levine, Adam Seth, Manville, Michael
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Measuring the satisfaction of multimodal travelers for local transit services in different urban contexts [PDF]

open access: yes, 2012
The importance of measuring customer satisfaction for a public transport service is apparent, even beyond more immediate marketing purposes. The present paper shows how satisfaction measures can be exploited to gain insights on the relationship between ...
Marco Diana, Diana, Marco
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

An Analysis of Public Transit Connectivity Index in Tehran. The Case Study: Tehran Multi-Modal Transit Network

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2016
Public transit is a major priority in modern management of large cities and metropolitan areas in particular. Public transit systems in such cities consist of a large number of nodes and lines which are represented by a complex network.
Amir Reza Mamdoohi, Hamid Zarei
doaj   +1 more source

“*I wouldn’t want to get on the bus*”: Older Adult Public Transit Use and Challenges during the COVID-19 Pandemic

open access: yesFindings, 2020
This paper reports on older adult (65+) public transit users’ experiences during the COVID-19 pandemic, a group more vulnerable to severe illness from the virus.
Lea Ravensbergen, Bruce Newbold
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Oregon Department of Transportation Public Transit

open access: yes, 2011
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 3, 2014)Mode of ...

core  

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