Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Södertörn University Publications
, 2017 This is a short introduction to Södertörn University Publications that Jonathan Robson (Publications Committee/Publications Department secretary) gave at the First Conference of the Association of European University Presses (AEUP). It was delivered on 16 May 2017 to delegates of European institutional publishing at Stockholm University Library.
openaire +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Changing Nature of the Faculty and Faculty Employment Practices [PDF]
, 2005 [Excerpt] The nature of faculty employment practices at American colleges and universities is changing rapidly. So too is the gender, racial and ethnic composition of American faculty members. These changes, along with the growing importance and costs of
Ehrenberg, Ronald G
core +2 more sources
Studying Ourselves: The Academic Labor Market [PDF]
, 2002 [Excerpt] The study of academic labor markets by economists goes back at least to Adam Smith’s suggestion in The Wealth of Nations that a professor’s compensation be tied to the number of students that enrolled in his classes. This paper focuses on three
Ehrenberg, Ronald G
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Reinventing the public mission of the research university in the Asian century: a gateway approach [PDF]
The recently released White Paper on Australia in the Asian Century reflected a consensus that higher education is at the cutting edge of our Asian engagement.
Kanishka Jayasuriya
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Efficiency of German Universities Some Evidence from Non-Parametric and Parametric Methods [PDF]
Due to tight public budget constraints, the efficiency of publicly financed universities in Germany is receiving increasing attention in the academic as well as in the public discourse.
Kempkes, Gerhard, Pohl, Carsten
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OPEN-SOURCE IMPLEMENTATION FOR E-LEARNING SYSTEM IN INDONESIAN UNIVERSITIES [PDF]
, 2009 University and educational organizations have different strategies in deploying E-learning systems, one of which is the use of open-source e-learning systems.
Jati, Handaru
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