Results 91 to 100 of about 12,387,034 (302)
Costs efficiency of the public universities
, 2013 In Bangladesh, like other developed countries, the public universities continue to face mounting pressure from the government to use resources in economically efficient ways in the face of increasing scarcity of funds.
Mamun, Md. Shamsul Arifeen Khan
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Universities: 2014 audit snapshot [PDF]
, 2015 This report sets out the key outcomes from financial audits of the eight universities and their 51 controlled entities for the year ending 31 December 2014.
Victorian Auditor-General
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Public perceptions of Australia’s universities [PDF]
, 2013 This report finds that universities are well regarded by the Australian public and business community.During 2012 Universities Australia reached out to the public and stakeholders to elicit their views and understanding of universities to assist in ...
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Innovate and prosper: ensuring Australia's future competitiveness through university-industry collaboration [PDF]
, 2015 Executive summary The continuation of Australia’s economic growth is under threat. In order to sustain the levels of prosperity we have previously experienced, we have to build on our competitive edge in key industries to remain globally competitive ...
Australian Industry Group +2 more
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Reinventing the public mission of the research university in the Asian century: a gateway approach [PDF]
, 2012 The recently released White Paper on Australia in the Asian Century reflected a consensus that higher education is at the cutting edge of our Asian engagement.
Kanishka Jayasuriya
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source