Results 81 to 90 of about 3,558,519 (308)

E-cigarette use in public places: Striking the right balance [PDF]

, 2016
First paragraph: The availability, marketing and use of electronic cigarettes or nicotine vapourisers is subject to a range of regulations across different countries, varying from the prohibition of sales and use, to little or no regulation.
McNeill, Ann, Britton, John, McNeill, Ann Denise; id_orcid, Hajek, P, Hajek, Peter, Britton, J, Bauld, Linda, Bauld, L, Dockrell, M, Dockrell, Martin, McNeill, A   +10 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Not in education, employment, or training (NEET) and risk of alcohol use disorder: a nationwide register-linkage study with 485 839 Swedish youths

BMJ Open, 2019
Objective To investigate to what extent being outside education, employment or training after completed secondary education in Sweden might affect the risk of subsequent alcohol use disorders (AUDs), with sociodemographic indicators, such as sex ...
Helio Manhica, Andreas Lundin, Anna-Karin Danielsson   +2 more
doaj   +1 more source

Car Use Habits: An Obstacle to the Use of Public Transportation? [PDF]

, 2008
It is often claimed that many drivers use their private car rather habitually. The claim gains credibility from the fact that travelling to many everyday destinations fulfils all the prerequisites for habit formation: it is recurring, performed under stable circumstances and produces rewarding consequences.
Møller, Berit Thorup, Thøgersen, John; id_orcid 0000-0003-0613-8062   +1 more
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Espacio público

ARQ, 2007
El actual prestigio de lo privado, la políticamente correcta pero devaluada condición pública y la ausencia de matices en las distinciones entre ambos urgen la definición de un código que asegure la continuidad de lo público en la ciudad. Bernardo Secchi
Elke Schlack
doaj  

Barriers and facilitators to medication-assisted treatment for cocaine use disorder among men who have sex with men: a qualitative study

Addiction Science & Clinical Practice
Background Rates of cocaine use disorder (CUD) among men who have sex with men (MSM) are high and rising. Among MSM, cocaine use is associated with negative socioeconomic, medical, and psychological outcomes.
Elaine Hsiang, Kishan Patel, Erin C. Wilson, Alexandrea Dunham, Janet Ikeda, Tim Matheson, Glenn-Milo Santos   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Unintentional benzodiazepine use and frequency of drug checking service utilization: a cross-sectional study

Harm Reduction Journal
Background There are increasing accounts of benzodiazepine adulteration and contamination in the unregulated drug supply in Canada and internationally.
Lauren Airth, Trevor Goodyear, Brandon D. L. Marshall, Cameron Grant, Mark Lysyshyn, Susan G. Sherman, Evan Wood, Lianping Ti   +7 more
doaj   +1 more source

Varieties in vaper identitys in a Norwegian context

Tobacco Induced Diseases, 2018
Background In this qualitative study, we analyze how users of e-cigarettes (vapers) articulate and express the meaning of vaping and their identity as vapers.
Rikke Tokle
doaj   +1 more source