Results 161 to 170 of about 3,170,256 (246)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
[Retracted] Effect of interventional embolotherapy on FHIT and p16 expression in hepatocellular carcinoma patients. [PDF]
Xu W, Qi X, Wang X, Sun J.
europepmc +1 more source
Reflections on Ending My Tenure as an Editor-in-Chief [PDF]
Won-Young Lee
doaj +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Knowledge mapping and visualization of immune checkpoint inhibitor-related pneumonitis: a bibliometric analysis. [PDF]
Jiang Y, Xu M, Xu S, Wu Q.
europepmc +1 more source
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli +4 more
wiley +1 more source
[Retracted] Nerve growth factor and its receptors on onset and diagnosis of ovarian cancer. [PDF]
Yu X, Liu Z, Hou R, Nie Y, Chen R.
europepmc +1 more source
[Retracted] MicroRNA‑363‑3p is downregulated in hepatocellular carcinoma and inhibits tumorigenesis by directly targeting specificity protein 1. [PDF]
Ying J, Yu X, Ma C, Zhang Y, Dong J.
europepmc +1 more source
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source

