Results 141 to 150 of about 5,988,794 (310)

Librarians’ strategic role in promoting teaching staff profiles on academic social networking sites

open access: yesDiscover Education
Academic libraries are pivotal in bolstering research endeavours by furnishing access to diverse resources and specialised services. This investigation explores the contribution of librarians in augmenting the visibility of teaching staff within higher ...
Christian Mubofu
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transforming digital health using the internet of things for personalized interoperable and secure healthcare systems

open access: yesDiscover Health Systems
The integration of the Internet of Things (IoT) into healthcare is enabling more connected, personalized, and data-driven medical services. This narrative review provides a comprehensive overview of healthcare IoT architectures, focusing on core ...
Fabian Chukwudi Ogenyi   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

In Their Own Words publication - text only [PDF]

open access: yes, 2012
This publication synthesises key findings from the the JISC Learner Experiences1 studies, drawing together themes from the Phase 1 reports1 and the five Learner Voice2 video case studies. Offering a variety of resources in a multimedia package, In Their

core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Spatially enabled society (FIG Publication No. 58) [PDF]

open access: yes, 2012
© 2012 The International Federation of Surveyors (FIG) and the Global Spatial Data Infrastructure Association (GSDI)Joint publication of FIG-Task Force on Spatially Enabled Society in cooperation with GSDI Association and with the support of Working ...

core  

Publication, publication, publication…

open access: yesThe Annals of The Royal College of Surgeons of England, 2014
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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