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mRNA-Based Vaccines [PDF]

open access: yesVaccines, 2021
Increases in the world’s population and population density promote the spread of emerging pathogens. Vaccines are the most cost-effective means of preventing this spread.
Frank Kowalzik   +5 more
doaj   +4 more sources

mRNA Vaccines against Flaviviruses [PDF]

open access: yesVaccines, 2021
Numerous vaccines have now been developed using the mRNA platform. In this approach, mRNA coding for a viral antigen is in vitro synthesized and injected into the host leading to exogenous protein expression and robust immune responses.
Clayton J. Wollner, Justin M. Richner
doaj   +4 more sources

Neo-Antigen mRNA Vaccines [PDF]

open access: yesVaccines, 2020
The interest in therapeutic cancer vaccines has caught enormous attention in recent years due to several breakthroughs in cancer research, among which the finding that successful checkpoint blockade treatments reinvigorate neo-antigen-specific T cells ...
Arthur Esprit   +5 more
doaj   +5 more sources

mRNA as a Therapeutics: Understanding mRNA Vaccines [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2022
Vaccination is one of the important approaches in the prevention and control of diseases. Although the capacity to present antigens other than the disease-specific antigen in the traditional vaccine composition provides a potential benefit by increasing ...
Ferdi Oğuz, Harika Atmaca
doaj   +3 more sources

Dangers of mRNA vaccines

open access: yesIndustrial Psychiatry Journal, 2021
“Necessity is the mother of invention:” An adage was brought to life with the emergence of the mRNA vaccine against the backdrop of the foreboding and mercurial COVID-19 pandemic.
Tahoora Ali   +4 more
doaj   +3 more sources

From COVID-19 to Cancer mRNA Vaccines: Moving From Bench to Clinic in the Vaccine Landscape

open access: yesFrontiers in Immunology, 2021
Recently, mRNA vaccines have become a significant type of therapeutic and have created new fields in the biopharmaceutical industry. mRNA vaccines are promising next-generation vaccines that have introduced a new age in vaccinology.
Chiranjib Chakraborty   +4 more
doaj   +3 more sources

A Comprehensive Review of mRNA Vaccines

open access: yesInternational Journal of Molecular Sciences, 2023
mRNA vaccines have been demonstrated as a powerful alternative to traditional conventional vaccines because of their high potency, safety and efficacy, capacity for rapid clinical development, and potential for rapid, low-cost manufacturing. These vaccines have progressed from being a mere curiosity to emerging as COVID-19 pandemic vaccine front ...
Vrinda Gote   +2 more
exaly   +3 more sources

mRNA Vaccines: Current Applications and Future Directions [PDF]

open access: yesMedComm
Messenger RNA (mRNA) vaccines, as a novel class of biotherapeutics, leverage mRNA technology to instruct cells to produce specific antigens, thereby inducing an immune response.
Jianmei Li   +8 more
doaj   +2 more sources

Research progress of mRNA vaccines for infectious diseases [PDF]

open access: yesEuropean Journal of Medical Research
mRNA vaccines for infectious diseases prevent diseases by stimulating the body to produce specific immune responses through mRNA molecules encoding pathogenic proteins.
Zhen Zhang   +5 more
doaj   +2 more sources

mRNA vaccine for cancer immunotherapy [PDF]

open access: yesMolecular Cancer, 2021
mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune
Lei Miao, Yu Zhang, Leaf Huang
doaj   +3 more sources

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