Results 31 to 40 of about 110,071 (192)
An Update on mRNA-Based Viral Vaccines
, 2021 With the success of COVID-19 vaccines, newly created mRNA vaccines against other infectious diseases are beginning to emerge. Here, we review the structural elements required for designing mRNA vaccine constructs for effective in vitro synthetic ...
Ki-Hye Kim +4 more
core +1 more source
Have mRNA vaccines sentenced DNA vaccines to death?
Expert Review of Vaccines, 2023 Introduction After receiving emergency approval during the COVID-19 pandemic, mRNA vaccines have taken center stage in the quest to enhance future vaccination strategies for both infectious diseases and cancer.
Alberto Cagigi, Bruno Douradinha
doaj +1 more source
Lipid nanoparticle-based mRNA vaccines in cancers: Current advances and future prospects
Frontiers in Immunology, 2022 Messenger RNA (mRNA) vaccines constitute an emerging therapeutic method with the advantages of high safety and efficiency as well as easy synthesis; thus, they have been widely used in various human diseases, especially in malignant cancers. However, the
Tao Huang +9 more
doaj +1 more source
mRNA vaccines: A novel weapon to control infectious diseases
Frontiers in Microbiology, 2022 Infectious diseases have always threatened human life, but with the development of vaccines, effective strategies for preventing and controlling these diseases have become available.
Yuying Tian +4 more
doaj +1 more source
Progress in researches on self-amplifying RNA vaccines
Zhongguo gonggong weisheng, 2023 Self-amplifying RNA (saRNA) vaccines are a new generation of mRNA vaccines. In addition to containing mRNA sequences encoding antigen proteins, saRNA vaccines also have unique self-amplifying elements, so self-amplification of antigen sequences can be ...
Shuo WANG, Jianmin LI
doaj +1 more source
mRNA Vaccines: The Dawn of a New Era of Cancer Immunotherapy
Frontiers in Immunology, 2022 mRNA therapy is a novel anticancer strategy based on in vitro transcription (IVT), which has potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in the early 21st century has promoted the application of mRNA ...
Zhuoya Deng +4 more
doaj +1 more source
, 2023 In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and transporting the mRNA payload into host cells. Despite their prominence in
Sathya N. Thulasi Raman +13 more
core +1 more source
mRNA vaccines: a new opportunity for malaria, tuberculosis and HIV
Frontiers in Immunology, 2023 The success of the first licensed mRNA-based vaccines against COVID-19 has created a widespread interest on mRNA technology for vaccinology. As expected, the number of mRNA vaccines in preclinical and clinical development increased exponentially since ...
Laura Matarazzo +3 more
doaj +1 more source
HIV mRNA Vaccines—Progress and Future Paths
, 2021 The SARS-CoV-2 pandemic introduced the world to a new type of vaccine based on mRNA encapsulated in lipid nanoparticles (LNPs). Instead of delivering antigenic proteins directly, an mRNA-based vaccine relies on the host’s cells to manufacture protein ...
Derek W. Cain +2 more
core +1 more source
mRNA vaccine: a potential therapeutic strategy
Molecular Cancer, 2021 mRNA vaccines have tremendous potential to fight against cancer and viral diseases due to superiorities in safety, efficacy and industrial production.
Yang Wang +5 more
doaj +1 more source