Results 141 to 150 of about 2,179,454 (288)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Exploring the landscape of lymphatic filariasis research in India: A scientometric analysis of two decades from 2000 to 2024. [PDF]
PLoS Negl Trop DisJabir M +4 more
europepmc +1 more source
Mapping Publication Trend of E-Government Development Index (Social Science Discipline Analysis)
Mohamad Sukarno, Dyah Mutiarin
openalex +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Updates on the Law of Diminishing Returns in the Integrated Plastic Surgery Residency Match. [PDF]
Plast Reconstr Surg Glob OpenElemosho A, Sarac BA, Janis JE.
europepmc +1 more source
Publication — "Le Néolithique du Nord de la France dans son contexte européen"
, 2011 IRHiS
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source