Results 141 to 150 of about 10,075,656 (346)
Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis +10 morewiley +1 more sourceTranscriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel +14 morewiley +1 more sourceIEEE Transactions on Information Theory Publication Information [PDF]
, 2022 Christina Fragouli, Parastoo Sadeghi, Edmund Yeh, Muriel dard, P Kumar, Matthieu Bloch, Junior Past, Senior Past, Mario Berta Quantum, Matthieu Security, Marco Dalai, Varun Jog, Thomas Johansson, Oliver Johnson, Shannon Theory, Information Measures, Daniel Katz, Mari Kobayashi Communications, Tobias Communications, Stefano Mancini, David Mitchell, Pradeep Kiran, Sarvepalli Quantum, Vincent Tan, Machine Learning, Statistics Ravi, Tandon Security, Tchamkerten Shannon, Antonia Wachter, Yang Sheng, Xinbing Communications, Wang, K Liu, Saifur Rahman, John Walz, Ellen Randall, Kathy Land, Stephen Phillips, Sergio Benedetto, David Koehler, James Matthews, Standards Association, Bruno Meyer, Deborah Cooper, Ali Sayed, Sophia Muirhead, Cherif Amirat, Chris Brantley, Karen Hawkins, Steven Heffner, Donna Hourican, Cecelia Jankowski, Geographic Activities, Konstantinos Karachalios, Ieee-Standards Association, Jamie Moesch, Thomas Siegert, Mary Ward-Callan +57 moreopenalex +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more sourceSub-series 2: Publications
, 1972 Special issue of a magazine with information about the Model Engineer Exhibition in London, including venue maps and event schedules, along with advertising and articles related to building model ...Model & Allied Publications Ltd.core Targeting Cellular Senescence for Healthy Aging: Advances in Senolytics and Senomorphics
Drug Design, Development and TherapyEsther Ugo Alum,1 Sylvester Chibueze Izah,2 Daniel Ejim Uti,1 Okechukwu Paul-Chima Ugwu,1 Peter A Betiang,3 Mariam Basajja,4 Regina Idu Ejemot-Nwadiaro5 1Department of Research Publications, Kampala International University, Kampala, Uganda; 2Department ...Alum EU, Izah SC, Uti DE, Ugwu OPC, Betiang PA, Basajja M, Ejemot-Nwadiaro RI +6 moredoaj IEEE Photonics Technology Letters publication information [PDF]
, 2019 Gabriella Cincotti, Brian Lee, Tetsuya Kawanishi, Dan M. Marom, Anna C. Peacock, Nobuhiko Nishiyama, Nicolas K. Fontaine, Seb J. Savory, Mark R. Hutchinson, M. Suzuki, Stephen E. Ralph, Jianquan Yao, Officers Jagadish, P Juodawlkis, Kent D. Choquette, Office-Douglas Menoni, René-Jean Essiambre, Membership Hawkins, Perry Ping Shum, Conferences Rusch, Affairs Li, Niloy K. Dutta, Chao Ning, A. D. Hawkins, M Sander, P Ioannone, David D. Sampson, Carl J. Williams, É Jos, Witold Moura, Hulya Fukuda, Kathleen Kramer, Francis Grosz, Geographic Activities, Joseph Lillie, Robert Fish, James Jefferies, Thomas T. Liu, Renuka Coughlin, Stephen Welby, Thomas Siegert, Business Administration, Cherif Amirat, Julie Cozin, Karen Hawkins, Donna Hourican, Cecelia Jankowski, Jamie Moesch, Michael Förster, Sophia Muirhead, Konstantinos Karachalios, Dawn Melley, Kevin Lisankie, Peter Tuohy, Jeffrey Cichocki, Neelam Khinvasara, Patrick Kempf, Peter Tuohy, Jeffrey Cichocki, Neelam Khinvasara, Patrick Kempf +60 moreopenalex +1 more sourceInteraction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen +9 morewiley +1 more source
