The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Relationships in the Organization of Knowledge Carol A. Bean and Rebecca Green (editors) (University of Tennessee and University of Maryland) Dordrecht: Kluwer Academic Publishers (Information science and knowledge management series, edited by J. Mackenzie Owen, volume 2), 2001, ix+232 pp; hardbound, ISBN 0-7923-6813-4, $97.00, £61.00, €90.00 [PDF]
Gregory Grefenstette
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
The Fragility of Quantum Information? [PDF]
We address the question whether there is a fundamental reason why quantum information is more fragile than classical information. We show that some answers can be found by considering the existence of quantum memories and their dimensional dependence.
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
_Precision Nanomedicine_ and its publisher _Andover House, Inc._ (Publisher) are committed to maintaining your confidence and trust with respect to your privacy.
Lajos P Balogh
doaj
The objective of this study is to explore the prevalence and characteristics of data sharing policies in library and information science (LIS) journals, focusing on their relationship with journal metrics, publisher volume (number of journals managed by ...
Eungi Kim+2 more
doaj +1 more source
Top notch: Evans, G Edward, and Ward, Patricia LayzellBeyond the basics: the management guide for library and information professionals.New York: Neal-Schuman Publishers, 2003. 325p US$59.95 soft ISBN 155570476X (available from DA Information Services) [PDF]
Bob Pymm
openalex +1 more source