Results 101 to 110 of about 3,875,406 (257)

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Physicists Thriving with Paperless Publishing

open access: yes, 2000
The Stanford Linear Accelerator Center (SLAC) and Deutsches Elektronen Synchrotron (DESY) libraries have been comprehensively cataloguing the High Energy Particle Physics (HEP) literature online since 1974. The core database, SPIRES-HEP, now indexes over
O'Connell, Heath B.
core  

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

WWJP: Where Would Jesus Publish?

open access: yes, 2010
Christians seek to follow the teachings of Jesus in every aspect of our lives. For academics who publish and librarians who purchase and license publications, where articles are published is important. The debates over scholarly communication, the future
Gee, C. William
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

THE MIND AND BRAIN SCHOLAR AS A HITCH-HIKER IN POST-GUTENBERG GALAXY: PUBLISHING AT 2000 AND BEYOND

open access: yes, 2000
Electronic journal (e-journal) publishing has started to change the ways we think about publish-ing. However, many scholars and scientists in the mind and brain sciences are still ignorant of the new possibilities and on-going debates.
Corre, Marianne   +2 more
core  

Publishing with undergraduates: some further observations [PDF]

open access: yes, 2015
This paper provides some additional observations on publishing with undergraduates following the short paper by Hartley (2014) in a previous issue of Psychology Teaching Review.
Griffiths, MD
core  

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