KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Physicists Thriving with Paperless Publishing
The Stanford Linear Accelerator Center (SLAC) and Deutsches Elektronen Synchrotron (DESY) libraries have been comprehensively cataloguing the High Energy Particle Physics (HEP) literature online since 1974. The core database, SPIRES-HEP, now indexes over
O'Connell, Heath B.
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Book Department:reviews : KNIFFIN, WILLIAM H., JR. The Savings Bank and Its Practical Work. Pp. vi, 551. Price $5.00. New York: The Bankers' Publishing Company [PDF]
Ernest Minor Patterson
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Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source
WWJP: Where Would Jesus Publish?
Christians seek to follow the teachings of Jesus in every aspect of our lives. For academics who publish and librarians who purchase and license publications, where articles are published is important. The debates over scholarly communication, the future
Gee, C. William
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Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
THE MIND AND BRAIN SCHOLAR AS A HITCH-HIKER IN POST-GUTENBERG GALAXY: PUBLISHING AT 2000 AND BEYOND
Electronic journal (e-journal) publishing has started to change the ways we think about publish-ing. However, many scholars and scientists in the mind and brain sciences are still ignorant of the new possibilities and on-going debates.
Corre, Marianne+2 more
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Publishing with undergraduates: some further observations [PDF]
This paper provides some additional observations on publishing with undergraduates following the short paper by Hartley (2014) in a previous issue of Psychology Teaching Review.
Griffiths, MD
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Gildersleeve's Latin Grammar - Gildersleeve's Latin Grammar. Third edition, revised and enlarged, by B. L. Gildersleeve and Gonzalez Lodge. (University Publishing Company: New York, etc. 1894. Macmillan & Co.: London. 1895.) [PDF]
E. A. Sonnenschein
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