Results 101 to 110 of about 13,377,628 (299)
Ten-year development of general practice in China: Opportunities and challenges
Chinese General Practice JournalObjective: To review the strengths and limitations of the development of general practice in China during the last decade (2010—2020) and to assess the opportunities and challenges for its future development.
Yang Hui +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Publishing and innovation : disruption in the Chinese ebook industry
, 2019 Is digital publishing leading to a paradigm shift or only replicating the print publishing systems in digital garb? This appears to be a key concern of the Chinese publishing industry in the internet age.
Ren, Xiang (Tony) (R18853)
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Railway, postal and telegraph map of the Middle Island, New Zealand [cartographic material] /
, 1889 Map of the South Island of New Zealand showing railways, railway stations, post and telegraph offices and postal routes. Relief shown by hachures.; From Vol. 3 of: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company.
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Publishing in Scotland: Reviewing the Fragile Revival
, 2008 A comparison of analyses of the Scottish publishing industry carried out in 1992, 2002 and 2007 underscores the fragility of the sector within a small country within the English-language community.
Sinclair, Marion +2 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Railway postal and telegraph map of the North Island, New Zealand 1889 [cartographic material] /
, 1889 Map of the North Island of New Zealand showing railways, railway stations, post and telegraph offices and postal routes. Relief shown by hachures.; From Vol. 3 of: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company
core
Stronger Together: Library-led Open Access Publishing in Scotland
027.7The purpose of this article is to look at library-led Open Access publishing initiatives across Scotland: particularly the Scottish Confederation of University and Research Libraries (SCURL) Open Hosting Shared Service and Scottish Universities Press ...
Dominique Walker, Rebecca Wojturska
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source