Results 141 to 150 of about 6,375,243 (383)

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Artificial Immune Systems - Models, algorithms and applications [PDF]

open access: yes, 2010
Copyright © 2010 Academic Research Publishing Agency.This article has been made available through the Brunel Open Access Publishing Fund.Artificial Immune Systems (AIS) are computational paradigms that belong to the computational intelligence family and ...
Abbod, MF, Al-Enezi, JR, Alsharhan, S
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

The influence of residential facilities on depression and frailty of the elderly in rural China: Evidence from the China health and retirement longitudinal study

open access: yesFrontiers of Architectural Research
In the context of rural revitalization and the increasing prevalence of aging population, the mental health of older adults in rural China has become an issue of widespread social concern.
Zhenhua Zheng   +4 more
doaj   +1 more source

Fortieth Anniversary of Publishing OPREE (REE)

open access: yes, 2020
Forty years ago in February 1981 the first issue of Occasional Papers on Religion in Eastern Europe appeared. The Executive Committee of the now defunct “Christians Associated for Relationship in Eastern Europe” of which I was a member and occasional ...
Mojzes, Paul B
core  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

General cost analysis for scholarly communication in Germany : results of the "Houghton Report" for Germany [PDF]

open access: yes, 2012
Management Summary: Conducted within the project “Economic Implications of New Models for Information Supply for Science and Research in Germany”, the Houghton Report for Germany provides a general cost and benefit analysis for scientific communication ...
Bernius, Steffen   +4 more
core  

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