Results 141 to 150 of about 7,017,523 (349)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
A modified inertial proximal minimization algorithm for structured nonconvex and nonsmooth problem
We introduce an enhanced inertial proximal minimization algorithm tailored for a category of structured nonconvex and nonsmooth optimization problems.
Zhonghui Xue, Qianfeng Ma
doaj +1 more source
This article is derived from the presentation titled “Mapping the World of Library Publishing: Revealing the Global Landscape and Collaborative Efforts” delivered during the panel discussion “Working Together to Expand Library Publishing Globally” at the
Guoying Liu, Ann Okerson, Qing Zou
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
VT-MFLV: Vision–Text Multimodal Feature Learning V Network for Medical Image Segmentation
Currently, existing multimodal segmentation methods face limitations in effectively leveraging medical text to guide visual feature learning. They often suffer from insufficient multimodal fusion and inadequate accuracy in fine-grained lesion ...
Wenju Wang +5 more
doaj +1 more source
The Idea of the Law Review: Scholarship, Prestige, and Open Access [PDF]
This essay was written as part of a Symposium on open access publishing for legal scholarship. It makes the claim that open access publishing models will succeed, or not, to the extent that they account for the existing economy of prestige that drives ...
Madison, Michael J
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Background: Current fMRI (functional magnetic resonance imaging)-driven brain information decoding for visual image reconstruction techniques faces issues such as poor structural fidelity, inadequate model generalization, and unnatural visual image ...
Wenju Wang +5 more
doaj +1 more source
Book review: a tale of two books: digital transformations are creeping across the face of academic life [PDF]
In response to Patrick Dunleavy’s posts on the future of e-publishing in academia, David Gauntlett writes on his experiences of publishing ebooks, and how Kindle self-publishing could be an approach which gets books to readers at a far more affordable ...
Gauntlett, David
core

