Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Defensive Publishing An Empirical Study [PDF]
Defensive Publishing denotes publication of an invention with the purpose of creating prior art, and thus preventing patents being granted on this invention. Although widely employed, it has hardly been investigated empirically.
Joachim Henkel, Stefanie Pangerl
core
When goodbye comes too soon: How to wrap up science projects quickly. [PDF]
PLoS BiolHagenauer MH +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Publishing and sharing sensitive data [PDF]
Sensitive data has often been excluded from discussions about data publication and sharing. It was believed that sharing sensitive data is not ethical or that it is too difficult to do safely.
Sarah Olesen
core
P. A. Shumskiy Osnovy strukturnogo ledovedeniya: Petrografiya presnogo l’da kak metod glyatsiologisheskogo issledovaniya [Principles of structural studies of ice: petrography of fresh water ice as a method of glaciological investigation]. Moscow, Izdatel’stvo Akademii Nauk SSSR [Publishing House of the Academy of Sciences of the U.S.S.R.], 1955. 492 pages, 119 illus. 22 cm. Price Roubles 22.25. [PDF]
, 1957 Andrzej Bauer
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Molecular Oncology, EarlyView.This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo +6 more
wiley +1 more source
The journey through disruptive loss and transformational gain: a co-creative single case study on writing and publishing after psychosis. [PDF]
Philos Ethics Humanit MedBrijs E +3 more
europepmc +1 more source