Results 221 to 230 of about 6,504,878 (383)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
An open letter to the NIH: value and costs in publishing. [PDF]
Jackson S +6 more
europepmc +1 more source
BRITTAIN PUBLISHING COY. (LONDON) LD. AND ANOTHERV.TRADE & COMMERCIAL PRESS LD. [PDF]
openalex +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
The transition to fully open access: a new era for the Journal of Clinical Monitoring and Computing. [PDF]
Flick M, Lobo FA.
europepmc +1 more source
Zülch, K. J.: Brain tumors; their biology and pathology. [Transl. From the German by Rothballer, A. B., & Olszweski, J.] New York, N.Y. Springer Publishing Co., Inc. 1957. 308 pp. $9.50 [PDF]
openalex +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Storm over science: predatory practices and the fight for research reliability. [PDF]
de Lorenzo V +6 more
europepmc +1 more source

