Celebrating milestones and embracing innovation: the next chapter for Drugs in Context. [PDF]
Drugs ContextAnderson SL, Mangoni AA, Torres T.
europepmc +1 more source
Differential and integral calculus, by F. Erwe. Translation by B. Fishel of the 1964 German edition. Hafner Publishing Co., New York, 1967, x + 494 pages. U.S. $9. 25. [PDF]
, 1969 Hugh Thurston
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Open science and transparency are our strongest tools in the fight against fraudulent publishing activities. [PDF]
PLoS MedLumbard H, Routledge D.
europepmc +1 more source
Cellular Control Mechanisms and Cancer. P. Emmelot and O. Mühlbock. American Elsevier Publishing Company, Inc., New York 10017, N. Y., $20.00 [PDF]
, 1965 Dean Burk
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
"I just very much love the journal": Understanding the community-led publishing landscape at the University of Cambridge. [PDF]
F1000ResMoore S, Wigdorowitz M.
europepmc +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
FEBS Open Bio, EarlyView.This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source