Results 91 to 100 of about 5,056,142 (323)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A method of assessing the quality of pharmaceutical market and industry reports as a source to study access to medicines [PDF]

open access: yes, 2016
This repository item contains a single issue of the Health and Development Discussion Papers, an informal working paper series that began publishing in 2002 by the Boston University Center for Global Health and Development.
Knox, Ryan P.   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Business Intelligence Challenges for Independent Game Publishing

open access: yesInternational Journal of Computer Games Technology, 2020
With the continuous development of the game industry, research in the game field is also deepening. Many interdisciplinary areas of knowledge and theory have been used to promote the development of the game industry.
Yanhui Su   +2 more
doaj   +1 more source

1. Publishing Industry

open access: yes, 2019
Jeffries’ article focuses on the increasing emphasis in the publishing sphere put upon digitisation and sustainability, and the transformation of books to ereaders, from paper to screen. She looks at this firstly from the perspective of the author, and then of the reader, focussing on the pressure that giants like Amazon are putting on publishers and ...
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Critical examination of the IEET measurement instrument for the assessment of textbook quality

open access: yesEkonomski Vjesnik, 2018
As is the case in other sectors of the creative industry, the publishing industry also evaluates its projects finalized in the form of products and services in the market of creative contents.
Ivana Ljevak Lebeda   +2 more
doaj  

First results of the SOAP project. Open access publishing in 2010

open access: yes, 2010
The SOAP (Study of Open Access Publishing) project has compiled data on the present offer for open access publishing in online peer-reviewed journals. Starting from the Directory of Open Access Journals, several sources of data are considered, including ...
Dallmeier-Tiessen, Suenje   +16 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Teaching the changing story [PDF]

open access: yes, 2007
This paper begins with a brief survey of the state of contemporary short fiction practice, with particular reference to McSweeneys Quarterly Concern, leading into a reflective account of pedagogical approaches to short fiction on Creative Writing degree ...
Hurley, UK
core  

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