Results 111 to 120 of about 1,395,322 (291)

The Minamata Convention and the future of mercury abatement [PDF]

open access: yes, 2013
This repository item contains a single issue of Issues in Brief, a series of policy briefs that began publishing in 2008 by the Boston University Frederick S.
Selin, Henrik
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

High Density Through Silicon Via (TSV) [PDF]

open access: yes, 2008
The Through Silicon Via (TSV) process developed by Silex provides down to 30 micrometers pitch for through wafer connections in up to 600 micrometers thick substrates. Integrated with MEMS designs it enables significantly reduced die size and true "Wafer
Bauer, Tomas, Rimskog, Magnus
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

BRAND PARTNERSHIPS AND COLLABORATION OF UKRAINIAN BOOK PUBLISHERS

open access: yesІнтегровані комунікації
A study of collaborations in the publishing business in Ukraine. Analysis of the impact of cooperation between publishing houses on market competition and cultural aspects. One of the most effective and common ways to convey information about a brand and
Tetiana Yezhyzhanska   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

A Survey of Religious Book Publishing with Implications for Collection Development in Christian College Libraries [PDF]

open access: yes, 2002
Discusses five sources of religious books. Profiles the religious book publishing industry. Describes a delicate balance between ministry and industry. Situates religious book publishing in its cultural context.
Smith, Gregory A
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Controlling the Flow of Information

open access: yesEarly Modern Low Countries
This article examines the political dimensions of printing privileges in the seventeenth-century Dutch Republic, analysing their impact on the dissemination of information, the development of the printing industry, and the nature of published works ...
Marius Buning
doaj   +1 more source

What Advertisers Want: A Hedonic Analysis of Advertising Rates in South African Consumer Magazines [PDF]

open access: yes
This article explores the role of circulation, readership and reader demographics in the determination of advertising rates in South African consumer magazines.
Nicolas Pietersma
core   +1 more source

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