Results 41 to 50 of about 13,047,952 (281)

Educational Publishing: An Industry in Transition in the Digital Age [PDF]

, 2014
The objective of this paper is twofold: first, to critically map educational publishing scholarship to date, particularly for the Australian market; and second, to reflect on an industry in transition, utilising the business theory of disruptive ...
Hargrave, J.
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Sleaze-O-Meter: Sexual Harassment in the Publishing Industry [PDF]

, 2018
Sexual harassment in publishing: the publishing industry has its own set of available responses to the wave of #MeToo revelations ...
Squires, Claire, Squires, C, Driscoll, Beth, Driscoll, B   +3 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Rethinking Book Industry Analysis : A Mesosystem Model for Strategic and Institutional Understanding

BiD: Textos Universitaris de Biblioteconomia i Documentació
Traditional analytical frameworks used to study the book industry—mainly linear, firm-centered, and value-chain based—offer limited capacity to capture the relational, institutional dynamics that characterize publishing ecosystems.
Iñaki Vázquez Álvarez
doaj   +1 more source

The strategy for the development of electronic publishing in small markets

Libellarium: Journal for the Research of Writing, Books, and Cultural Heritage Institutions, 2014
This paper analyses technological trends which affect the business models in the publishing industry and create innovative publishing products which reflect the reader's needs in the digital environment.
Ivona Despot, Tomislav Jakopec
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Scottish Archive of Print and Publishing History Records [PDF]

, 2002
'It's important that we remember the past is not just dry facts and statistics but also the detailed lives of real people. SAPPHIRE aims to give a voice to these lives.' The Scottish Archive of Print and Publishing History Records (SAPPHIRE), an ...
Finkelstein, David, Bromage, Sarah, McCleery, Alistair   +2 more
core   +5 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source