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Synthesis of Derivatives of the Monoterpenoid Pulegone

Chemistry of Natural Compounds, 2015
N-containing derivatives that were promising as biologically active compounds were synthesized via a series of transformations of the monoterpenoid pulegone isolated from Ziziphora clinopodioides essential oil.
N. G. Kozlov   +3 more
openaire   +1 more source

Different Stereoselectivity in the Reduction of Pulegone by Mentha Species

Planta Medica, 2001
Aqueous solutions of [2H]-labeled pulegone enantiomers were fed to Mentha spicata ssp. spicata L. and Mentha spicata ssp. crispata L. shoot tip and first leaf pair. After solid phase microextraction the essential oil was analysed with enantioselective multidimensional gas chromatography/mass spectrometry.
S, Fuchs, T, Beck, A, Mosandl
openaire   +2 more sources

The favorskii rearrangement of pulegone oxide

Tetrahedron, 1967
Abstract The stereoisomeric pulegone oxides I and II undergo a stereospecific Favorskii rearrangement when treated with sodium methoxide in refluxing glyme. The major products are identified by spectroscopic measurements and by conversion to pulegenic esters (X A,B) and puleganolides (XIII A,B).
W. Reusch, P. Mattison
openaire   +1 more source

Metabolic fate ofS-(-)-pulegone in rat

Xenobiotica, 1998
1. S-(-)-pulegone was administered orally to rat (250 mg/kg) and the nature of the urinary metabolites was investigated. Eleven metabolites, namely S-(-)-menthofuran, piperitone, piperitenone, p-cresol, 5-hydroxypulegone, 4-methylcyclohexenone, 3-methylcyclohexanone, isopulegone, pulegol, 7-hydroxypiperitone and benzoic acid, have been isolated from ...
Madyastha, KM, Gaikwad, NW
openaire   +2 more sources

Stability of pulegone and thujone in ethanolic solution

Journal of Agricultural and Food Chemistry, 1990
The study aims to obtain information about the safety of essential oils from mint or sage. The stability of the monoterpene ketones (R)-(+) pulegone and alpha- and beta-thujone in aqueous-ethanolic solutions was measured by using a model experimental system.
Otmar Froehlich, Takayuki Shibamoto
openaire   +1 more source

Inhibition of acetylcholinesterases by pulegone-1,2-epoxide

Pesticide Biochemistry and Physiology, 1985
Abstract Toxicological observations indicate that pulegone-1,2-epoxide, isolated from the medicinal plant, poleo (Lippia stoechadifolia), is an insect neurotoxin. These observations prompted studies of the action of pulegone-1,2-epoxide on acetylcholinesterase activity.
Dawn L. Grundy, Cecil C. Still
openaire   +1 more source

Biological activities of pulegone

1998
High antibacterial and antifungal activity of pulegone has been confirmed by broth dilution method. It has also been found that pulegone has short-term stimulating effect on diuresis in rats.
Pepeljnjak, Stjepan   +3 more
openaire  

The Metabolism of (R)-(+)-Pulegone, a Toxic Monoterpene

1992
(R)-(+)-Pulegone is a major monoterpene constituent of pennyroyal oil, a mint oil obtained from the leaves of plants Mentha pulegiwn or Hedeoma pulegoides (1). Pennyroyal oil is widely used as a fragrance and flavoring agent (2), and has been used, based on folklore, as a herbal medicine to control menses and terminate pregnancy (3).
Sidney D. Nelson   +5 more
openaire   +1 more source

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