Results 101 to 110 of about 489,904 (300)

Eigenproblem formulation for electromechanical microsystem pull-in voltage optimization

open access: yes, 2013
Electrostatic actuators are often used in MEMS since they are relatively easy to manufacture and provide a short response time. Previous studies have already considered topology optimization of such micro-actuators like the work by Raulli and Maute [1 ...
Van Miegroet, Laurent   +4 more
core  

The stability and pull-in voltage of electrostatic parallel-plate actuators in liquid solutions

open access: yesJournal of Micromechanics and Microengineering, 2006
This paper deals with parallel-plate electrostatic actuators in liquids. We study the stability conditions of such actuators and show that the pull-in effect can be shifted beyond one-third of the gap, and can even be suppressed. We demonstrate that the insulating layers of the actuator plates, which are originally designed to avoid any current ...
Rollier, Anne-Sophie   +3 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Conversor CC-CC trifásico ZVS PWM de três níveis [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Esta tese propõe uma topologia de conversor CC-CC trifásico de três níveis, modulado por largura de pulso e com comutação ...
Agostini Junior, Eloi
core  

A micromachined voltage controlled oscillator using the pull-in mechanism of electrostatic actuation

open access: yesIEICE Electronics Express, 2009
This study presents a microelectromechanical voltage controlled oscillator based on the pull-in electromechanical contact of an electrostatic actuator. Micromachining process of nickel electroplating on a silicon substrate was used to develop an electrostatic torsion plate mechanism (200µm × 200µm in area, 15µm in thickness) that could be mechanically ...
Yi, Yuheon   +2 more
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Effects of van der Waals Force and Thermal Stresses on Pull-in Instability of Clamped Rectangular Microplates

open access: yesSensors, 2008
We study the influence of von Karman nonlinearity, van der Waals force, and a athermal stresses on pull-in instability and small vibrations of electrostatically actuated mi-croplates.
Davide Spinello   +2 more
doaj  

Design and Demonstration of Radio Frequency Micro Electro-Mechanical System Switches with Meandered Beams for Reduced Actuation Voltage

open access: yesProceedings
In this paper, a class of three series ohmic switches is presented, including its design principles, the simulation results, and the outcomes of the measurements performed on the first batch of fabricated samples.
Girolamo Tagliapietra   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Pull-in instability of nano-switches using nonlocal elasticity theory

open access: yes, 2008
This paper investigates the pull-in instability of nano-switches subjected to an electrostatic force due to an applied voltage and intermolecular force within the framework of nonlocal elasticity theory to account for the small scale effect.
Jie Yang (18030766)   +2 more
core  

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