Results 121 to 130 of about 6,973,275 (314)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2018 The material is pulled on a specially designed fixture without holding it from the sides. The base plate moves freely and combines the vice, which has a freely determined angle. It is structured to support on the upper surface of the material with plates
Takeo Nagura (4446865) +4 more
core +1 more source
The Effect of Bar Diameter on Bond Stress of Geopolymer Concrete with Pull-out Test
Journal of Civil EngineeringGeopolymer concrete, an eco-friendly alternative, employs silica, alumina, and alkaline activators. While wet mixing has been extensively studied, its limitations, such as impracticality, quick setting, and low workability, are overcome by the dry mixing
Khansa Fadilah Ashara +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Numerical modelling of cyclic pull-out behaviors of embedded plate anchors in saturated soft clay
, 2014 As a foundation for deep-water floating offshore structures, the embedded plate anchor should withstand the complicated marine conditions involving the cyclic loads.
Hu C(胡存), Gao FP(高福平)
core
BuildingsTo improve the pull-out bearing capacity of the anchor plate support system, a support system with series-connected anchor plates was proposed. Based on the Winkler foundation model, a theoretical analysis method for the pull-out resistance–displacement ...
Jie Liu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Theoretical model of piezoelectric fibre pull-out
, 2015 A theoretical model of a single piezoelectric fibre pull-out is developed to study the interaction between fibre deformation, pull-out stress and corresponding electrical field.
Liu, Hong-Yuan +2 more
core +1 more source