Results 111 to 120 of about 6,973,275 (314)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Aderência aço-concreto: simulação numéricadosensaios de arranchamento pull-out e APULOT usando o programa ATENA

open access: yesRevista IBRACON de Estruturas e Materiais, 2014
A aderência entre o aço e o concreto é fundamental para a existência das estruturas de concreto armado, uma vez que os dois materiais atuamem conjunto para absorver os esforços solicitantes. O fenômeno da aderência é considerado complexo no que se refere
A. J. Tavares   +3 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Numerical Modeling of Fiber Pull-Out Micromechanics in Concrete Matrix Composites

open access: yes
The presented research work compares numerical results of single fiber pull-out of elastic matrix with the experimental data obtained the for single steel fiber pulled out of high-strength concrete matrix were.
Krasņikovs, Andrejs   +4 more
core  

Pull-down assay using biotinylated BENDA.

open access: yes, 2017
(A) Chemical structure of Bio-BENDA. (B) Pull-down assay using Bio-BENDA. MDA-MB-468 cells were treated with Bio-BENDA in the presence or absence of excess free BENDA for 4 h.
Yukie Inoue (3709453)   +7 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Alternate Title: Pull It Out, Pull It Out, Pull It Out

open access: yes, 1916
First Line: Take me to the dentist right away!First Line of Chorus: I've got a sweet tooth bothering me, pull it out, pull it out, pull it outTitle of Larger Work: Step This WayKey: B Flat ...

core  

The effect of baseband impedance termination on the linearity of GaN HEMTs

open access: yes, 2010
This paper demonstrates the significant effect of baseband impedance termination on the linearity performance of a 10W GaN HEMT device driven to deliver a peak envelope power of approximately 40dBm. The paper also proposes a further refinement to a state-
Woodington, S.   +21 more
core   +1 more source

Does the Bone Cement Affect Miniscrew Stability?

open access: yesTurkish Journal of Orthodontics, 2013
Objective:The purpose of this study was to determine whether bone cement increased the resistance of miniscrews against pull-out and shear forces.Materials and Method:Sixty commercially available miniscrews were placed into bovine bone samples (one each)
Mustafa B. Ateş   +5 more
doaj   +1 more source

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