Results 61 to 70 of about 2,671,300 (345)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Modification of Equation for Calculating the Bond Stress Between Steel Bars and Concrete

Buildings
The bond between steel bars and concrete is a fundamental aspect of reinforced concrete, ensuring the efficient transfer of forces between the two materials and guaranteeing their compatibility and composite action.
Xiaosan Yin, Jimin Li, Shidong Tang, Yuzhou Sun, Md. Mashiur Rahman   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Experimental and numerical studies on progressive debonding of grouted rock bolts

International Journal of Mining Science and Technology, 2022
Understanding the mechanism of progressive debonding of bolts is of great significance for underground safety. In this paper, both laboratory experiment and numerical simulation of the pull-out tests were performed.
Hao Shi, Lei Song, Houquan Zhang, Wenlong Chen, Huasheng Lin, Danqi Li, Guozhu Wang, Huayun Zhao   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Study on bond performance parameters of GFRP bars based on pull-out test

四川大学学报. 自然科学版, 2021
To obtain reasonable bond performance parameters of GFRP bars, the indoor pull-out test and numerical simulation are used to study the bond performance between GFRP bars and mortars.
ZHANG Xin, LI Hua-Yun, ZHANG Zhi-Qiang, DENG Lai   +3 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Towards Selecting an Optimal Bonding Test Method for Rebar–Concrete: Comparison Between Pull-Out Test and Full-Beam Test

Buildings
There are many methods for evaluating the bond behavior between rebar and concrete. For certain experimental purposes, selecting the ideal method for testing the rebar–concrete bonding properties is often a controversial problem.
Sisi Chao, Chenghua Li, Jiahong Dong, Ziliang Lu   +3 more
doaj   +1 more source

STUDY THE EFFECT OF STEEL WIRES PRE-TENSION ON THE BENDING AND ADHESION PROPERTIES OF BEAD PLY IN RUBBER TIRES

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ, 2018
Tires are considered important components of the vehicle by which the vehicle can move on the road. The continuous development in the transportation requires improving tires to suit the modern requirements of the transportation.
Ahmed A. Kadhem, Mujid H. Enad, Ali S. Yasir   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source