Results 31 to 40 of about 100,967 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Railway crossing with adjustable pulling force as function of loading [PDF]
In this paper presents the concept of controlling the pulling force as a function of loading of railway crossing that was modelled as a discrete-continuous system.
Jan TARGOSZ, Tomasz BURATOWSKI
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Genetic Algorithm and ANN for Estimation of SPIV of Micro Beams [PDF]
In this paper, the static pull-in instability (SPIV) of beam-type micro-electromechanical systems is theoretically investigated. Herein, modified strain gradient theory in conjunction with Euler–Bernoulli beam theory have been used for mathematical ...
M. Heidari
doaj
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Simulation and Application to Measure Comparable Performance of Push,Pull and Hybrid Manufacturing Systems [PDF]
In this paper we are going to integrate the most popular production systems nowadaysthat is; push ,pull production system, ,then we compare the performance of the integratedproduction model or the hybrid outcome system to push and pull, by introduce a ...
Hussein S. Ketan, Nahidh Jaffar K
doaj +1 more source
The general behavior of pull production systems: The allocation problems [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nureddin Kirkavak, Cemal Dinçer
openaire +5 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

