Results 41 to 50 of about 100,967 (263)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background: Despite high coverage of indoor interventions like insecticide-treated nets, mosquito-borne infections persist, partly because of outdoor-biting, early-biting and insecticide-resistant vectors. Push-pull systems, where mosquitoes are repelled
Arnold S. Mmbando +6 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
KOMPARASI SISTEM MANUFAKTUR PUSH DAN PULL MELALUI PENDEKATAN SIMULASI
Manufacturing systems that are often classified as push and pull often invite question: "How far do the differences between those two systems exist?" Many researches have been carried out but succinct answer to the above question is always difficult to ...
Eric Wibisono
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Generalized analysis of dynamic pull-in for singular magMEMS and MEMS oscillators
The exact pull-in threshold for single-degree-of-freedom actuator models arising in the design of micro-electro-mechanical systems (MEMS) is derived analytically by studying exact solutions to trinomial equations of arbitrary degree.
Piotr Skrzypacz +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Simulation of a Plant-Wide Inventory Pull System [PDF]
Successful implementation of inventory pull (kanban) systems has become a widely discussed topic in recent years. This paper examines one such effort which uses simulation modeling as a means to quantitatively design such a system. The Normalize area is responsible for beat treating raw material for Delco Chassis wheel spindle bearing products.
openaire +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Scheduling and sequencing problems for pull/push and mixed system
In this research, we revised and extended the mathematical model that was developed by Herer and Masin (1997), the modified model can be applied for push and pull systems into integrating scheduling and sequencing problems ...
Nguyễn Ngọc Bình Phương +2 more
doaj

