Results 61 to 70 of about 100,967 (263)

Research on Flow Field Characteristics Affected by Obstacles of Pull-Push Ventilation System of Plating Tanks through Numerical Simulation

MATEC Web of Conferences, 2016
Pull-push ventilation system, with high capture efficiency, is universally used to capture contaminants from containment generation where can’t be enclosed and where the working area is large.
Hu Hong, Yi Can-nan
doaj   +1 more source

Governing the emissive properties of 4-aminobiphenyl-2-pyrimidine push-pull systems via the restricted torsion of N,N-disubstituted amino groups. [PDF]

Front Chem, 2023
Cortés-Villena A, Soriano-Díaz I, Domínguez M, Vidal M, Rojas P, Aliaga C, Giussani A, Doménech-Carbó A, Ortí E, Galian RE, Pérez-Prieto J.   +10 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Towards Keyword-based Pull Recommendation Systems

Proceedings of the 18th International Conference on Enterprise Information Systems, 2016
Due to the high availability of data, users are frequently overloaded with a huge amount of alternatives when they need to choose a particular item. This has motivated an increased interest in research on recommendation systems, which filter the options and provide users with suggestions about specific elements (e.g., movies, restaurants ...
María del Carmen Rodríguez-Hernández, Sergio Ilarri, Raquel Trillo Lado, Francesco Guerra 0001   +3 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Containment Control of Fractional-Order Time-Delay Multi-Agent Systems Employing a Fully Distributed Pull-Based Event-Triggered Approach

Fractal and Fractional
The current study explores the fully distributed containment control problem of fractional-order time-delay multi-agent systems by introducing a novel pull-based dynamic event-triggered approach.
Jing Bai, Yaxuan Cai, Xue Xia, Xiaohe Li, Guoguang Wen   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

“PUSH” AND “PULL” SYSTEMS IN SUPPLY CHAIN MANAGEMENT. CORRELATIVE APPROACHES IN THE MILITARY FIELD [PDF]

Journal of Defense Resources Management, 2016
The increase in economic, social and security risks is currently determined by the resource crisis on the one hand, as well as by the economic competition and global military challenges on the other hand, which amplifies instability and jeopardizes the
Gheorghe Minculete, Polixenia Olar
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source