Results 71 to 80 of about 100,967 (263)
MATEC Web of Conferences, 2018 The main objective of this paper is pioneering an innovative tactic for the synchronization of multi-stage, multi-line, production system. This tactic is mainly depends on the optimization policy, by means of distinct event simulation process for ...
Srikanth O. +2 more
doaj +2 more sources
Bottleneck Oriented Card-Based Production Control for Push Repetitive Manufacturing Systems
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013 One of the major problems of the push Repetitive Manufacturing Systems (RMS) is the Work In Process (WIP) buildups between the stations due to the push nature of the flow of material. Card-based pull or push-pull production control systems offered smooth
Muhammad Haris AZIZ +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Power Pull: an unconditionally stable active Load-Pull measurement system
, 1998 For today's communication circuits optimum operational conditions for almost every Tx power amplifier is one of the most important parameters. Only this will offer maximum power added efficiency and output power. For the experimental determination of these conditions load-pull measurements are the best solution. To compensate losses of the setup for on-
Koether, D., Sporkmann, Th.
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
California Agriculture, 1966 SPRINKLER IRRIGATION for tree crops in the San Joaquin Valley has increased rapidly during the past ten years, particularly in areas planted to citrus. While no exact figures are obtainable, it is estimated that more than 20,000 of the 100,000 acres in ...
R Schade
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source