Results 201 to 210 of about 1,417,462 (268)

Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension in an Adolescent With a Novel Frameshift Variant in PROS1. [PDF]

Pulm Circ
Fujii H, Isobe S, Taniguchi Y, Tamura Y.
europepmc   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Heart-Lung Interactions in Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction. [PDF]

Compr Physiol
Prabala P, Raza F, Chesler NC.
europepmc   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Establishment of a prediction model for malignant probability of pulmonary nodules in an adenocarcinoma-predominant cohort. [PDF]

PeerJ
Li F, Yu X, Xu K, Zhang G.
europepmc   +1 more source

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

Advanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao, Xuemei Sun, He Li, Bangming Wang, Mengting Pan, Zhen Ma, Rong‐Mei Kong, Weiheng Kong, Yan Zhao, Fengli Qu   +9 more
wiley   +1 more source

Pulmonary vasodilator therapy in COPD-associated pulmonary hypertension: A real-world case series of 14 patients confirmed by right heart catheterization. [PDF]

Respir Med Case Rep
Vera Ricaurte M, Kosak Lopez E, Geller A, Leguizamon R, Lam J, Srikulmontri T, Helena Siqueira Tavares de Melo M, Stavola T, Malin J, Martinez-Manzano JM, Pacheco E.   +10 more
europepmc   +1 more source

Simultaneous saddle pulmonary embolism and right atrial thrombus managed with ICE-guided dual suction Thrombectomy. [PDF]

Oxf Med Case Reports
Sabah I, Saife S, Nouri A, Khaddash T, Bhanushali S, Khaddash I, Shamoon F.   +6 more
europepmc   +1 more source

Pulmonary fibrosis: evolving therapeutic pipeline. [PDF]

BMJ Med
Shannon L, Islam S, Hilary B, Murphy G, Bailey S, Rooney R, Chaudhuri N.   +6 more
europepmc   +1 more source