Results 171 to 180 of about 1,155,700 (284)

Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease [PDF]

open access: gold, 2008
Mervyn J. Merrilees   +5 more
openalex   +1 more source

Electrical Impedance Tomography–Guided Airway Clearance in Elderly Patients With Severe Pneumonia: A Prospective Study

open access: yesThe Clinical Respiratory Journal, Volume 19, Issue 7, July 2025.
EIT‐guided personalized airway clearance significantly improves outcomes in elderly severe pneumonia patients. Real‐time electrical impedance tomography (EIT) optimized secretion clearance through dynamic adjustment of posture, percussion, and breathing techniques.
Jiaping Zhao   +8 more
wiley   +1 more source

Human Alveolar Macrophages Detect SARS‐CoV‐2 Envelope Protein Through TLR2 and TLR4 and Secrete Cytokines in Response

open access: yesImmunology, Volume 175, Issue 3, Page 391-401, July 2025.
Alveolar macrophages (AMs)—the most numerous immune cells of the lung—respond to viral infections by secreting cytokines to summon other immune cells. We investigated whether AMs recognize SARS‐CoV‐2 proteins and how they respond. AMs did not sense spike protein but did recognize envelope protein via the pattern recognition receptors TLR2 and TLR4 ...
Conor Grant   +6 more
wiley   +1 more source

ILC2 Diversity, Location, and Function in Pulmonary Disease

open access: yesImmunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma   +2 more
wiley   +1 more source

Skin development in the gray short‐tailed opossum (Monodelphis domestica)—From skin respiration to thermoregulation

open access: yesJournal of Anatomy, Volume 247, Issue 1, Page 108-133, July 2025.
The skin development in the gray short‐tailed opossum (Monodelphis domestica) has been examined using histological, morphometric, and μCT methods. During a long period of postnatal development, the structural differentiation of the skin results in a functional shift from transcutaneous gas exchange to thermoregulation in later life. Abstract Marsupials
Kirsten Ferner
wiley   +1 more source

De Novo Missense Variant in Bovine WDR33 Associated With a Complex Syndromic Form of Cleft Palate With Pentalogy of Fallot and Internal Hydrocephalus

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Cleft palate (CP) is a congenital defect characterized by an opening in the palate. Two crossbred paternal half‐sibs with a complex syndrome including CP were identified. Hypothesis/Objectives Characterize disease phenotype and evaluate the genetic cause of the observed syndrome.
Marilena Bolcato   +5 more
wiley   +1 more source

Mechanically Tunable Poly(Ethylene Glycol) Diacrylate Hydrogels Reveal Stiffness‐Related Impairments in Capillary Sprouting in Experimental Lung Fibrosis

open access: yesMicrocirculation, Volume 32, Issue 5, July 2025.
ABSTRACT Objective Synthetic hydrogels that support 3D cell culture are widely used as platforms for modeling disease, such as tissue fibrosis, which leads to mechanical stiffening of the extracellular matrix (ECM). To interrogate how mechanical stiffness of the ECM affects microvascular remodeling, we developed a bioactive poly(ethylene glycol ...
Julie Leonard‐Duke   +7 more
wiley   +1 more source

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