Ultrastructure of pulmonary alveoli and macrophages in experimental Legionnaires' disease
The Journal of Pathology, 1983AbstractGuinea pigs, rhesus monkeys and marmosets infected with Legionella pneumophila in small particle aerosols developed an acute fibrinopurulent bronchopneumonia. Changes from 24 hr included exudation into alveoli of protein‐rich, often fibrinous fluid and many polymorphonuclear leucocytes (PMN) and macrophages.
A. Baskerville+4 more
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Pulmonary administration of integrin-nanoparticles regenerates collapsed alveoli
Journal of Controlled Release, 2014Chronic obstructive pulmonary disease (COPD) is an intractable pulmonary disease, causes widespread and irreversible alveoli collapse. In search of a treatment target molecule, which is able to regenerate collapsed alveoli, we sought to identify a factor that induces differentiation in human alveolar epithelial stem cells using all-trans retinoic acid (
Hiroshi Kubo+4 more
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Distribution of Inhaled Metal Oxide Particles in Pulmonary Alveoli
Archives of Internal Medicine, 1971The phagocytic response of alveolar cells is a significant factor in determining the pulmonary distribution and fate of inhaled, insoluble particles. The type I alveolar epithelium and alveolar macrophage readily phagocytized inhaled nickel monoxide and chromic oxide particles with 80% and 91%, respectively, of alveolar deposits being found in ...
Alfred P. Wehner+4 more
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Gaseous diffusion from alveoli into pulmonary arteries
Journal of Applied Physiology, 1964In 40 patients, during right heart catheterization a catheter with a platinum tip electrode was wedged in a branch of the pulmonary artery. With the electrode acting as part of a potentiometer, signals were recorded following single inhalations of hydrogen.
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Adrenomedullin Regenerates Alveoli and Vasculature in Elastase-induced Pulmonary Emphysema in Mice [PDF]
Adrenomedullin, a potent vasodilator peptide, regulates cell growth and survival. However, whether adrenomedullin contributes to lung regeneration remains unknown.To investigate whether adrenomedullin influences the kinetics of bone marrow cells, and whether adrenomedullin promotes regeneration of alveoli and vasculature and thereby improves lung ...
Takefumi Itoh+8 more
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Marcello Malpighi and the discovery of the pulmonary capillaries and alveoli
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2013Marcello Malpighi (1628–1694) was an Italian scientist who made outstanding contributions in many areas, including the anatomical basis of respiration in amphibia, mammals, and insects and also in the very different fields of embryology and botany. He was one of the first biologists to make use of the newly invented microscope and is best known as the ...
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Postnatal development of pulmonary alveoli: modulation in rats by thyroid hormones
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1986We studied the effect of thyroid hormones on the postnatal development of the gas exchange region of rat lungs. Treatment with triiodothyronine (T3, 0.1 microgram . g body wt-1 . day-1) accelerated the increase of the surface-to-volume ratio (S/V) and surface area (Sa) and decrease of the mean chord length (Lm) of the gas exchange structures of pups ...
G. D. Massaro, N. Teich, D Massaro
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Lymphatics of the Human Pulmonary Alveoli: Preliminary Report
Chest, 1970The subpleural lymphatics of a normal human lung were injected with a dilute, green-colored latex solution after the lung had been made edematous by normal saline infusions. The tracheobronchial tree was then filled with a white latex, following which the preparation was submerged in concentrated HCl to achieve corrosion of the tissues.
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AN IMPROVED MATHEMATICAL MODEL OF HYDRODYNAMICAL SELF-CLEANSING OF PULMONARY ALVEOLI
The Annals of Occupational Hygiene, 1993In the present paper we postulate a hydrodynamical mechanism of pulmonary alveoli cleansing and explain the role of the lung surfactant system in this phenomenon. Then a new, significantly refined mathematical model of the dynamics of the layer lining alveoli is derived and tested numerically in order to check theoretically whether the mechanism ...
Leon Gradoń, Albert Podgórski
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Innervation of pulmonary alveoli of the mouse lung: An electron microscopic study
American Journal of Anatomy, 1972AbstractThe nerve supply to the alveolar ducts and alveoli of mouse lungs was studied with the electron microscope. In the alveolar ducts, nerve bundles consisting of as many as nine unmyelinated axons surrounded by connective tissue fibers were usually located in the interstitium surrounding the openings of the alveoli.
Clayton G. Loosli+3 more
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