Results 151 to 160 of about 560,791 (351)

Inflammation in pulmonary arterial hypertension [PDF]

, 2003
Peter Dorfmüller, Frédéric Perros, Karl Balabanian, Marc Humbert   +3 more
openalex   +1 more source

Comparison of Fixed‐Dose Clopidogrel/Asetylsalicylic Acid Combination and Standard Loading Strategy During Percutaneous Coronary Intervention in Chronic Coronary Syndrome

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Dual antiplatelet therapy (DAPT), comprising acetylsalicylic acid and a P2Y12 receptor inhibitor such as clopidogrel, is the cornerstone of management in patients undergoing percutaneous coronary intervention (PCI). While conventional loading doses of acetylsalicylic acid and clopidogrel are well established, there is limited ...
Ahmet Anıl Başkurt, Oktay Şenöz, Yusuf Demir, Eren Ozan Bakır, Ferhat Siyamend Yurdam, Ecem Gürses, İlhan Koyuncu, Ahmet Erseçgin, Saadet Aydın, Zeynep Yapan Emren, İlker Gül   +10 more
wiley   +1 more source

Correction of hypercoagulability and amelioration of pulmonary arterial hypertension by chronic blood transfusion in an asplenic hemoglobin E/β-thalassemia patient [PDF]

, 2003
Vichai Atichartakarn, Suporn Chuncharunee, Pakorn Chandanamattha, Khanchit Likittanasombat, Katcharin Aryurachai   +4 more
openalex   +1 more source

Pulmonary arterial hypertension and pregnancy.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013
PubMed ID ...
Kayikcioglu, Meral, Kultursay, Hakan, Ergenoglu, Mete, Musayev, Oktay, Mogulkoc, Nesrin, Gunusen, Ilkben, Akisu, Mete, Kultursay, Nilgun, Terek, Demet, Yalaz, Mehmet   +9 more
openaire   +4 more sources

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

ChemMedChem, EarlyView.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali, Samet Poyraz, Samet Belveren, Senanur Taş, Mehmet Ali Tamer, Naciye Yaktubay Döndaş, H. Ali Döndaş, Jose Miguel Sansano   +7 more
wiley   +1 more source

Macitentan and morbidity and mortality in pulmonary arterial hypertension.

New England Journal of Medicine, 2013
T. Pulido, I. Adzerikho, R. N. Channick, M. Delcroix, N. Galiè, H. Ghofrani, P. Jansa, Z. Jing, Franck-Olivier Le Brun, S. Mehta, Camilla Mittelholzer, L. Perchenet, B. Sastry, O. Sitbon, R. Souza, A. Torbicki, Xiaofeng Zeng, L. J. Rubin, G. Simonneau   +18 more
semanticscholar   +1 more source

MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]

, 2005
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J., E. Kenneth Weir, M.D., López Barneo, José, Stephen L. Archer, M.D   +3 more
core  

Raised plasma concentrations of brain natriuretic peptide in pulmonary arterial hypertension

, 1995
Neeraj Prasad, Chim C. Lang, Howard M. McAlpine, Anna Maria Choy, Thomas M. MacDonald, Allan D. Struthers   +5 more
openalex   +1 more source

Development of Keap1‐Nrf2 Protein–Protein Interaction Inhibitor Activating Intracellular Nrf2 Based on the Naphthalene‐2‐acetamide Scaffold, and its Anti‐Inflammatory Effects

ChemMedChem, EarlyView.
Pyrrolidine‐type naphthalene‐2‐acetamide compound 5i inhibits Kelch‐like ECH‐associated protein 1 (Keap1)‐nuclear factor erythroid 2‐related factor 2 (Nrf2) protein–protein interaction by binding to the Keap1‐DC domain; it subsequently activates intracellular Nrf2 and induces Nrf2‐target genes.
Daisuke Yasuda, Kai Toyoshima, Koujin Kojima, Hanako Ishida, Kazuma Kaitoh, Riyo Imamura, Kayoko Kanamitsu, Hirotatsu Kojima, Megumi Funakoshi‐Tago, Masanori Osawa, Tomoyuki Ohe, Tomoya Hirano   +11 more
wiley   +1 more source

Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension.

New England Journal of Medicine, 2015
N. Galiè, J. Barberà, A. Frost, H. Ghofrani, M. Hoeper, V. McLaughlin, A. Peacock, G. Simonneau, J. Vachiéry, E. Grünig, R. Oudiz, A. Vonk-Noordegraaf, R. White, C. Blair, H. Gillies, K. L. Miller, Julia H N Harris, J. Langley, L. Rubin   +18 more
semanticscholar   +1 more source