Results 171 to 180 of about 173,364 (256)

Mental Disorders and Quality of Life in Patients With Pulmonary Arterial Hypertension Treated With Sotatercept. [PDF]

Pulm Circ
Fuge J, Olsson KM, Remmert K, Stapel B, Kamp JC, Park DH, Hoeper MM, Winter L, Kahl KG.   +8 more
europepmc   +1 more source

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

KLF6 activation marks an angiogenic and apoptosis resistant endothelial phenotype in pulmonary arterial hypertension. [PDF]

Commun Biol
Alharbi R, Keles M, Fernandes N, Maude H, Fellows A, Williams RD, Chen CN, Lambie N, Matthews N, Al-Sahaf M, Barnett SN, Guo M, Zhao L, Lawrie A, Whitsett JA, Cebola I, Wojciak-Stothard B.   +16 more
europepmc   +1 more source

Optimizing polytherapy management for Dravet syndrome in the United States: A National Expert Consensus

Epilepsia Open, EarlyView.
ABSTRACT Objectives Dravet syndrome (DS) is a severe, drug‐resistant developmental and epileptic encephalopathy (DEE) that requires polytherapy for adequate seizure control. The need to combine multiple antiseizure medications (ASMs), together with variability in seizure types, safety considerations, and evolving patient needs, makes treatment ...
Elaine Wirrell, Joseph Sullivan
wiley   +1 more source

Defect in lysosomal enzyme trafficking and sorting is associated with irreversibility of pulmonary arterial hypertension. [PDF]

Front Cardiovasc Med
Xiao G, Meng Y, Du Z, Liu Z, Yu H, Wang H, Nie L, Liu X, Lan X, Duan Y, Xiong J, Liu Z.   +11 more
europepmc   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Pulmonary Arterial Hypertension: From Molecular Basis to Therapeutic Approaches. [PDF]

Biomedicines
Adão R.
europepmc   +1 more source

Coronary pathophysiology in idiopathic pulmonary arterial hypertension. [PDF]

JCI Insight
Boland E, Freeman MG, Corcoran DS, Ford TJ, Hennigan B, Collison D, Llucià-Valldeperas A, de Man FS, Balachandran KP, Johnson M, Church C, Berry C.   +11 more
europepmc   +1 more source

Predictive Value of the Pulmonary Artery Pulsatility Index in Pulmonary Arterial Hypertension: REVEAL Analysis. [PDF]

Cardiol Res
Ruopp NF, Farber HW, Rahman M, Kapur NK, Safdar Z.   +4 more
europepmc   +1 more source