Results 201 to 210 of about 173,364 (256)

Sotatercept administration in a young infant with severe pulmonary arterial hypertension: A case report. [PDF]

Front Pediatr
Rathakrishnan AV, Torgeson J, Beshish A, Bogenschutz MC, Balasubramaniam V, Lamers LJ.   +5 more
europepmc   +1 more source

Compressed Sensing‐Accelerated 3.0 T Noncontrast‐Enhanced CMRA: Diagnostic Efficacy for Coronary Artery Stenosis

iRADIOLOGY, EarlyView.
This bar chart illustrates the diagnostic performance of coronary magnetic resonance angiography (CMRA) for detecting ≥ 50.00% coronary artery stenosis at the segment, vessel, and patient levels, including sensitivity, specificity, positive predictive value, negative predictive value, and accuracy.
Zhengfu Wang, Yue Zhu, Yi Yin, Zewang Li, Mingming Huang, Bo Gao   +5 more
wiley   +1 more source

Rodatristat ethyl decreases activity in pulmonary arterial hypertension: results from the ELEVATE-2 trial. [PDF]

Ann Am Thorac Soc
Lachant DJ, Sahay S, Block R, Ossip D, Denning J, Lazarus HM, Parsley E, White RJ.   +7 more
europepmc   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Hemodynamic and Thrombotic Vulnerability in Pulmonary Arterial Hypertension at High Altitude: Multivariable Predictors of Mortality. [PDF]

Medicina (Kaunas)
Conde-Camacho R, Tuta-Quintero E, Mora-Barrero A, Bastidas-Goyes A, Giraldo-Cadavid LF.   +4 more
europepmc   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Sotatercept in TBX4 Associated Heritable Pulmonary Arterial Hypertension: A Case Report of a Super Responder. [PDF]

Pulm Circ
Schneijdenberg JW, van den Bosch AE, Kap ME, Kauling RM, Chandoesing PP, van den Toorn LM, Mathot BJ, Koudstaal T, Boomars KA.   +8 more
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Baseline state for pulmonary vasculature with pulmonary arterial hypertension: effect of geometric remodeling and metabolic shift. [PDF]

Biomech Model Mechanobiol
Mullagura HN, Gharahi H, Figueroa CA, Baek S.   +3 more
europepmc   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura   +15 more
wiley   +1 more source